Excellent, excellent,
excellent article here by Gina Kolata:
Genes Take Charge, and Diets Fall by the Wayside
I think I'll probably be referring to it as often as I referred to the Atul Gawande article ("we are a species that has evolved to survive starvation, not resist abundance") and I thought about just copying and pasting the whole thing somewhere since the Gawande article faded from the web to the point that I had only my own old quotes of it to rely on. But I have "Times Select" (for New York Times subscribers) and so should be able to access this indefinitely.
It's somewhat depressing, yes, but I find it fascinating and useful in terms of combating how fat people tend to be viewed, plus the aspect of deciding where resrouces would be most useful.
It also demonstrates what an accomplishment it is for people like Mac, who have taken off a lot of weight and kept it off -- that's DIFFICULT, and she's doing an amazing job of it.