I don't think WB is making a New Gods film purely because of Thanos. Both DC and Marvel, and many other popular franchises, already had films with CGI characters in major roles, performed by actors in motion capture suits.
Besides, Darkseid will be part of the new version of 2017's Justice League, to be released on HBO MAX on 2021 (Darkseid was cut from the theatrical version of the film due to a director change mid-production) They released a new teaser featuring the villain.
I was just bringing up 2D Amiga animation as an example. Eric Schwartz, the animator and cartoonist I told you about, was famous for producing a bunch of 2D Amiga animated cartoons. He is the underground artist who created Amy the Squirrel and Sabrina the Skunk. He has a series of Amy the Squirrel and Sabrina Online comics. I've seen some of his animated cartoons, comics and other work on his official website. Some of his cartoons can be seen on YouTube.
I discovered this guy's work a long time ago, around the time I was in art school.