Computer Animation = 3D CGI
I didn't think I had to specify.
Avatar and Avengers: Endgame are the most successful films in history, and both feature live action actors interacting with CGI characters.
According to Wikipedia, Cool World was a major financial flop that killed Bakshi's film career.
Mary Poppins Returns was successful, but the animated sequence was only a small part of the film and the film's success relied heavily on the music, the cast, and nostalgia.