Gosh, this is shading into the surreal.
Your topic title is which one will hurt him MOST. Inherent in that -- they'll all hurt him, to varying degrees. Inherent in
that -- as factors that will hurt him to varying degrees, they're all negative.
Let me try a thought experiment with you, LSM. I say that oranges are a fruit. Then I say I hate all fruit. Would you be justified in concluding that I hate oranges? How would you react if I responded with, "Now hold on there just one minute, I never said I hated oranges! Don't go putting words in my mouth!"