@ossobuco,
Back in 1902 or there abouts, I was a student in bacteriology and we were taken as a class to Olive View Hospital. This was in the early sixties, when TB was still a giant deal. (I'd worked on a survey about it as a teen in the late fifties). The thing was, we walked into a gigantic room filled with guinea pigs in pens. I can still almost see it like a photograph, and hear it.
Later, I worked with guinea pigs in a milder way, nothing awful, not nothing, but, still.. anyway, that was all for producing antiglobulins.
My boss let us like the guinea pigs, looking back, tacky science, I suppose. Two of us carried them in our lab coat pockets once in a while, so dear.
Not long later, I started with the sneezing, but that could have had many other triggers.
Olive View Hospital was a mess after an earthquake.