Talk to wife lovingly and tell her your concern.
My issue a bit trickier. We are married 25 yrs and have grown children and we both held high corporate positions. We never had any issue with our relationship and I was comatosed 2 years. Another year physiotherapy to get me functioning again.
I woke up and saw a transformed wife ... gym (Mon-Fri) and working late most nights. Once, I woke up at 10.30pm and she was not in. Got back around 12.30am. She said she was out counselling Ruby. I asked for her phone to check on the meeting appointment. She refused, saying "private matter. Go to bed, sick man!". Next day I asked if she wants a separation. She said "No. Who will take care of you?"
I was surprised she doesn't feel happy I am better now. She still comes back around 12 midnight (most nights) citing company motivation with different teams. I kissed her good night and tasted alcohol in her lips.
Last week normal ... back by 7pm and had dinner together. Still being watchful.