I found this article on Pepe Le Pew:
Pepé has never become truly famous, as Bugs Bunny and Daffy Duck have. Instead, he has attracted some controversy over the years. The idea of a skunk intent on wooing a lady or getting a kiss is not very popular with the adult generation of today, as it might teach kids lessons that they should not learn. In other words, chasing someone whom you find attractive, particularly women at times, is not acceptable. He could be seen as sexist as he treats the female cat as a sex object in most of the cartoons, but simply wants a girlfriend. Therefore, it gives the wrong impression that it's okay to treat someone like that when you want a relationship; you wanted a boyfriend/girlfriend but you see him/her more as a sexual desire to you than a simple romantic relationship, as well as giving children the wrong idea that men are sexual predators or rapists while women are seen as victims and sex objects. In one cartoon, For Scentimental Reasons, a female cat who was mistaken for a skunk becomes a sex predator herself and Pepe becomes the victim, thus reversing the roles. this illustrates that women can be predators and men as the victims and sex objects. A rarity is that women can also rape men but if men call for help, society will ridicule them as it is not regarded as masculine. However, it is strange how the murder attempts of Wile E. Coyote have never truly become as controversial as Pepe has.
Pepé's sexuality has also been put into question for some fans. At first he was heterosexual, but in his debut episode and his cameo in "Dog Pounded" portrays him falling for other men as well, indicating that he may either be bisexual (or may be suspected as a homosexual) or is somewhat a lonely character who wants to be loved.