How do start an awereness foundation?

@High Seas,

Yes I know for sure Smile

H8Y-MC-HBBO its what it says on pill bottle

@peter jeffrey cobb,

peter jeffrey cobb wrote:

Yes I know for sure H8Y-MC-HBBO its what it says on pill bottle

But that's only the original name of the study, not the name of any of the medications. Read this on my last link (bold added by me):

Quote:

Responsible Party: Eli Lilly ( Chief Medical Officer )
ClinicalTrials.gov Identifier: NCT01129674
Other Study ID Numbers: 11960, H8Y-MC-HBBO
Study First Received: May 21, 2010
Last Updated: December 13, 2010

Let me know if you're getting tired Smile

1 Reply

@High Seas,

ooh wait sorry here its the name isLY2140023 80mg taken 2 times daily Smile

1 Reply

@peter jeffrey cobb,

Peter - sorry have to go for today, but will look in again tomorrow. This is the relevant part of the study description:

Quote:

The study includes 2 treatment periods. Study Period I will begin at patient randomization (enrollment into Study HBBO) and continue through the first 2 years of treatment. Study Period II will be only for patients randomized to treatment with LY2140023, and will begin after the patient has completed the second year of treatment. Patients who qualify for enrollment will be randomized in a 3:1 ratio (LY2140023 versus standard of care, respectively) into 2 treatment groups: flexible, twice-daily dose of LY2140023 or standard-of-care (olanzapine, risperidone, aripiprazole, or quetiapine). Those assigned to LY2140023 will have the option to continue on LY2140023 after 2 years if deemed appropriate by the investigator.

You say you're out of the double-blind test period, but why not ask your doctor and find out for sure? I bolded the 5 drug names.

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@peter jeffrey cobb,

Aha! All is clear now Smile

Yes, that's the new one.

Those older ones had such horrible side effects people would rather live with the hallucinations. How are you feeling on this new medication?

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@High Seas,

from my perspective its not working ):

1 Reply

@peter jeffrey cobb,

Have you tried any of the others named here?

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@High Seas,

before the study the drugs i was taking was olanzapine and lithium

1 Reply

@peter jeffrey cobb,

1. How old are you?
2. Did those other 2 drugs make you feel better than the new one?

1 Reply

@High Seas,

im 40 years old and the others made me feel like i was under a narcotic...... kind of druken state. But it did work in the manner that my mind was slowed down enough to were I was having one though at a time. Hmmmm kind of like when youre so drunk that you have to concetrate to acomplish an action. Does that make sense to you? Its like if someone is in pain.... you can numb the pain but you are not realy addressing the cause of it.

1 Reply

@peter jeffrey cobb,

If you want to drop out of this study there are many other ongoing ones, including some with no drugs at all, but their selection criteria aren't the same as Eli Lilly's. Here is the most promising of the non-drug clinical trials:
----------------------------------------------

27
Recruiting
Transcranial Direct Current Brain Stimulation to Treat Patients With Childhood-Onset Schizophrenia
Conditions: Childhood Onset Psychotic Disorders; Schizophrenia; Psychosis; Mental Disorders Mental Disorder Diagnosed in Childhood
Intervention: Behavioral: Electrical Polarization

http://clinicaltrials.gov/ct2/results?cond=%22Schizophrenia%22&pg=2
-------------------------------------------------------

Really, really must run now - have a good day Smile

1 Reply

@High Seas,

hmm yes I understand this trial probaly wont help me. But i am hopping by participating and giving my imput it will futher advance the treament of people like myself Smile

hope you have a great day Smile

1 Reply

@peter jeffrey cobb,

Hi Peter - saw you started another thread where you had to explain your health situation all over again. You got good advice there: people will post if they can help you, but they can't be expected to hunt around for all the new threads you start on the same or similar topics. Stay on one thread for each topic.

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@peter jeffrey cobb,

peter jeffrey cobb wrote:

Before i was under a medication that basicaly felt like narcordic it made me drosy and light headed. It slow my thought process enough to were I could focus longer on one subject at a time. It worked in that sense but who realy wants to live the rest of their lifes under the influence....... hmm i guess the best way to explain it is being drunk. If you were told that you were gona have to be drunk for the rest of your life i belive most people would say " hey come on youre gotta be kidding there has to be another way" Well the sad thruth is that to my knoledge there isnt. So felling hopeless i went and registered in clinical trials for a new drug. Unfortanly I im not having much success with it ): But if evrey person that took the trial said ok im just gona tink about me and if it dont work ill leave the trials......... well then the researchers wouldnt have much to go on and we would not advance any in the cure for this disease. Makes sense? Tank you for posting

If Lilly's new drug isn't helping you, you're not helping anybody else by sticking with it. How it works, very briefly, is by blocking the glutamate receptors in the brain; previous drugs blocked dopamine and/or serotonin receptors causing terrible side effects.

As a study participant you are obviously under medical supervision - go ahead and ask your doctor next time you see him/her whether it makes sense to continue with this drug or is it time to try something else? These are the symptoms the drug tries to alleviate:

Quote:

A * Positive symptoms:
1. hallucinations,
2. delusions,
3. agitation,
4. disorganised thinking

B * Negative symptoms:
1. introversion,
2. apathy,
3. low self-esteem leading to personal neglect and more rarely
4. catatonia

C * Cognitive symptoms:
1. poor memory,
2. attention deficit,
3. executive dysfunction

D * Affective symptoms:
1. depression,
2. elation,
3. suicidal ideation

List is from company site for LY2140023:
http://www.drugdevelopment-technology.com/projects/elililleyantisycotic/
Try to go through the list and decide which item in your own condition is better/worse than it was with the previous treatments you had - saying the drug isn't working for you probably needs a bit more explanation.

Another important result obvious from that list is that items A4, B3, C1, C2, C3, D1, D3 afflict many, many other people who are not schizophrenics; A3 afflicts many geriatric patients as well as people on street drugs and non-psychiatric medications.

So you see many, many, more millions out there (in addition to the few million people worldwide who suffer from schizophrenia) would be helped if this new approach to blocking brain receptors turns out to work. But if it doesn't the sooner that's found out the better.

I copied the list from the link and numbered and bolded the items to make them clearer for you. Come back and post your answers here - talking to others obviously helps everybody get some perspective and clarity in his thinking - look forward to reading you again Smile

1 Reply

@High Seas,

Wow thank you for going out of your way for this. I realy do appretiated Smile

. Hmmmm Being that this is study, I am being evaluated by a battery of expecialists on the field. Wouldnt they say something if the belived it was time for me to change to a new medication? When I go for my monthly visits I tell them that to me it dont appear to be working ( I do have to use words like appear because of my disease the line between reality and dilusions are a fine one Smile

) Wouldnt they if it was best for this trial remove me from it or at least change onto a new type of treatment?

1 Reply

@peter jeffrey cobb,

You wouldn't be in that study to begin with unless you met the strict criteria for participants, specifically:

Quote:

# Patients must be considered reliable, have a level of understanding sufficient to perform all tests and examinations required by the protocol, and be willing to perform all study procedures
# Patients must be able to understand the nature of the study and have given their informed consent

All these experts and their batteries of tests won't get anywhere unless they get a response from you. I don't know how detailed their examinations are, but what have you got to lose by being more specific on what, exactly, isn't working for you?

I've no doubt at all these experts genuinely want to help you, but for that they need your input. Go through the list - it's their list, not mine. See how many items you can address as being better or worse, take the answers with you next time you see them. I'll be back in a few days but I'll post a link to this thread on your other thread, so interested people can find it. Good luck to you and goodbye for now:)

1 Reply

@High Seas,

Ok thank you verry much. See you.......well more apropiettly .... read from in a few days Smile

1 Reply

@peter jeffrey cobb,

Just looking in to see how you're doing - will be able to take some time Sunday and copy your posts from the other threads to this one here so people have all your info in one location. The other posters you spoke to are nice people; but this running threads in parallel is confusing for anybody and it will be easier for them to follow everything on one thread. Meanwhile, are you in touch with the VA hospital nearest you - which I think is Miami, but I could be wrong - because they do have outreach volunteers who could visit you if you ask them. Or you could call the medics from the Lilly drug testing group. Don't give up, OK? Smile

1 Reply

@High Seas,

Doing ok

and yays thanks. Dont want to confuse anyone Smile

And Im not quite sure I know how to give up. Smile

)

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@peter jeffrey cobb,

This is a cut-and-paste from your new thread. As so many others have told you on that thread already there's absolutely no need to apologize to anybody. I'm back as promised and hope you can print out this thread - to which I will add - and take it with you next time you go for your monthly checkup.

Quote:

I would like to apologize to this comunity. After some reading I finaly realized that this is a place for people with the highest education. I dont even hold a coledge degree. I can barely spell anymore. I am a very sick person. My schizophrenia has been getting progressively worse. I have auditory dilusions. Like discutions in my head. Hmmm well since you cant see my side of the screen, let me give you an exaple. Sometimes I go weeks without taking a shower because I first gotta win an argument in my head about why is it more important for me to shower than to conserve water. Sounds silly huh. But thats why they are called dilusions. Its hard for me to do something as simple as taking a ride in a car. I go into a panick mode. I have no social life (well that one should be self explanatory) The few days I spend in this community, I read alot of stuff. Sounds harmeless right? Well the thing is alot of what I read becomes a question open for discution in my head. Ok still sounds harmeless right? Well these discutions go on till im so mentally exausted That I just passed out, then I wake up and the process repeats itself. That happened to me 4 times today alone. And well on top of that some of these are not logical thoughts. For example I read something that hex wrote. And my voices conviced me this was a personal statement. Well you can read the posts to see how that ended up. My apoligies again hex. And also to all that I may haved showed disrepect. I will try to stick to my topic were high seas is atempting to help me with my medication problem. I am scared to death my last medication basicaly made me zombie like. I cant realy see a future. dont consist of being zombied out, hospitalized, incarserated, and few other examples that consist more of delusions then reality. If youre a medical stundent, going into the research field for this disease. Well my prayers are with you I hope you are the one that finaly finds a cure. Well before anyone assumes that this is a bait tread. I want to assure this is not. I am sincere in my apology to this community. Thank you for taking the time to read my apology

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