paint pigments , used by artists until fairly recently, were a dogs breakfast of toxic compounds (mostly metal salts and oxides)
Consider how artists like Michelangelo,Leonardo, and more recent artists like Van Gogh, were known to keep the bristle sides of their brushes in their
mouths while painting.
Some colors and their original pigment bases included
bright greens-from verdigris formed by soaking Copper plates in wine vinegar
Greens and blues-from coarsely ground copper carbonate compounds
Ultramarine-finely ground Lazurite from Afghanistan
Prussian blue-cyanide compound
Yellows-from compounds of tin and lead oxide
white-from lead oxide
red-Mercuric sulfide compounds
vermillion-Cinnabar (mercury sulfide) and orpiment (Arsenous sulfide) Of course there was always Paris Green a carbonate of Arsenic, however, this compound was used mostly in the decorative arts 9like for wall paints and papers)
i found a web site that gives some more details of old pigments
Today our colors are less toxic but may not be as light fast as these early salt pigments. Of the very best pigments made today, I believe that only Sennelier still uses some of the "less toxic " metal combinations, like Chromes and Copper.
MICHELANGELO FORUM