Hello my friend,
I accidently stumbled upon this post and really hope that by now you have already discussed this with your wife. If not then you should do that first.
You should mention that how important she is in your life (sometimes women need more security, expressing your love for your wife gives them the security they need). Openly share how her attitude is affecting you. This is very important because sometime people do thing unintentionally.
Relationship between husband and wife is very sensitive and it takes many sacrifices and good understanding from both. It becomes more sensitive and stronger ( in most cases) after kids. So you guys have to discuss openly what bothers you and her and how you can address your problems as adults. If this works out between you guys then that's great.
If not, I would suggest that talk to her about counseling. When a third person hear problems from both sides, the opinion of third person is normally unbiased and provides a good solution to problem. Make sure this third person is neutral and not a close friend of any of you.
If counseling does not work then involve family. I am saying this because as adults you should be able to solve your own problems. If parents know about these issue, they get worried and we should try to keep our parents away from our problems as much as possible. This is the secret to get respect from your parents and keep them happy. Every parent want happiness for their kids and they can resolve issues based on their experience and bond which they have created with you guys over the years. Just listen to your parents as long as you feel like their efforts and advise will keep you guys together. What I want to say is that don't part your ways with your wife because your parents hate her and only need a reason to convince you to divorce her.
If that does not work either, then separate yourself for few months to see how that will impact your, her and your kids life. Make sure this separation is mutual agreement and trial based to see the consequences of any extreme decision on you, your wife and kids. Sometimes, seeing problems make people appreciate what they used to have. If this does not work either, then it is best for you to separate your ways.
I really hope your relationship works out but if it does not then you will know that you did your best to keep the relationship and it was just not meant to work out for some good reasons.
All the best.