Is the author talking about a picture of fours factors A,B,C,D (A = what disables and kills people across countries, B=time, C=age, and D=sex)?
Context:
The Global Burden of Disease: a critical resource for informed policymaking
Everyone, all over the world, deserves to live a long life in full health. In order to achieve this goal, we need a comprehensive picture of
what disables and kills people across countries, time, age, and sex. The Global Burden of Disease (GBD) provides a tool to quantify health loss from hundreds of diseases, injuries, and risk factors, so that health systems can be improved and disparities can be eliminated.
More:
http://www.healthdata.org/gbd/about