If it's not set in stone...
Being in a wheelchair is one element out of many.
There are people in wheelchairs who are seen as "options," and others who aren't. But that's a lot more about the other elements than the wheelchair per se.
Are you good looking? Athletic? (I know a lot of guys in wheelchairs who have v. nice arms.) Nice guy? Sense of humor? Confident? Good listener? Etc., etc.
I'm not in a wheelchair but have been very active in the disability community for a long time, and I know all kinds of people in wheelchairs who are in relationships, in various permutations. (The man's in a wheelchair, the woman's not; the woman's in a wheelchair and the man's not; they're both in wheelchairs; they're both women; they're both men; etc.!)