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You may be one of those whose physiology can tolerate these classes of alkaloids. then again you may be one of those who, unannouced, can suffer severe reactions one day out of the blue.
Perhaps the fact that ones body accomodates to a certain dosge is why some folks take to jacking up their pills, until they reach a critical level.
That is why the bottles are regulated via the FDA with this ... C.01.025. Both the inner and the outer labels of a drug that carry a recommended single or daily dosage or a statement of concentration in excess of the limits provided by C.01.021 shall carry a caution that the product is to be used only on the advice of a physician.
This is also why the prudent person like myself who I believe to be in the majority, follows both instructions and common sense and lays off the ephedra when it reaches a point that it's not doing to job at the recommended dose.
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losing weight takes discipline and time. Apparently we, as a society need to short circuit the process.
Again, used properly ephreda is another tool in the box. I had gotten out of the habit of being active and the ephreda got me off my ass. I'm back in the habit now, and work out, run, and watch my diet with or without it.
Cold as it sounds, the people who have misused the drug and killed themselves are simply Darwin award candidates as far as I'm concerned. I am sorry for their loss and the loss of their loved ones, but to ban the drug is absolutely ridiculous.[/[/b]I]
Well, it is 1:25 here in God's country and I am going to run. I took some ephreda about an hour and a half ago.
If I should drop over dead while running, by all means and with my blessing, gloat.
It would be pretty funny actually.
Well I ran, I emptied my work van, and now I'm heading upstairs to lift.
great day.
wenchelina, thanks for the five foot book shelf, I promise you, I will read a few cause their titles interest me. Ive gotta ask you, is ephedrine(IN its packaging as a weight control sUPPLEMENT), not regulated by the FDA as an OTC drug but as a food supplement? If thats the case USP limits dont even apply. As you know , there are many supplements that are not only of limited use , but some are toxic in certain conditions(the case of St Johns Wort comes to mind). The comment you made about Acetomenophen or Ibuprofen intox are quite real, i knowl. Im involved in a number of environmental studies (as a water quality specialist) that are monitoring the estrogen mims in the Chesapeake and the big 2 are acetominophen and , ordinary surfactants. However, acetomin . is regulated as an oTC and dosage and efficacy, shelf life, etc, is assured.
my understanding is that ephedra has no such labeling , in fact it contains statements that
"FDA has not evaluated the the statements herein..."
or something like that
I noticed from some of the titles that phys properties can be enhanced by interactions of ephedra and something else . eg, one title was thermogenic Properties of ephedrine and methylxanthine...( Im not sure of the pharmaceutical usage of the term thermogenic, in crystal chemistry we use the term to mean "heat producing" )
Does that mean that if you wash down your ephedra with cocoa, youll get a different reaction? methylxanthine is theobromine no?
Show me the present status of how ephedra is regulated for content. dosage etc. im here to learn, but Everything Ive seen in the Forensic Academy Journal based on post morts, has suggested that SCD onset was consistent with ephedrine intoxication.
im well aware of the acute side effects that many drugs ( OTC DRUGS) manifest. However, using a risk analogy is (and you know it if youre a scientist) often an insurance carriers reasoning thats merely used to "take the heat off" the poison under the scope. For USP produced drugs,Those side effects are listed on contraindications sheets and often the intoxication outcomes also result from misdosing (like people who take warfarin also using aspirin for arthritis) resulting in major internal bleeding. but at least the USP defines the effective content in each capsule and the formulae are more heavily regulated. I dont see that with ephedra.
Ill retract this if you have better information. (Anyway, even if Im dead wrong I love to loudly argue with people who dont immediately go for insults, that way being right or wrong is a great road to enlightenment)
I worked for a number of Pharma facilities in Puerto Rico, I headed up a team of engineers and scientists who were trying to control the discharge of pharma products (like diazepam) into the marine environment,(so you may know the company) so I say this with humble certainty. ThePharma- Industry makes its product decisions upon income acceptable risk(In otherwords, how many lawsuits or deaths can we tolerate and still reap our target profits). In the case of ephedra ,If the USP dictates the dosage and FDA has a chnace to regulate this as a drug, then Id have to agree with all of the advocacy positions and chalk it up to "acceptable risk" AT this point I need convincing .
Hell, Ill bet (and Ive never seen a bottle of many of these "fat burners', because , to me, theyre snake oil
, but ill bet the Pharmacopia sections that youve quoted, may not even apply to such a food supplement.
