Michael_S wrote:Vinsan,
thank you for the links .
Let's cut to the chase. How is the H5N1 virus diagnosed?
Through an antibodi test? don't antibodies usually mean you have a resistance to a disease? At best all this can tell you is the person has been in contact with H5N1.
How about through a PCR test. The flaw here is, why do you need to amplify the germs millions of times to detect them. Normally wouldn't one expect to see millions of germs without the need for amplification to signify illness?
The presence of antibodies mean that you have been exposed to an antigen which stimulates the production of the antibody. In this case the antigen is a virus. The presence of an antibody might, but does not necessarily, mean you no longer have the virus. Take HIV for instance, a person who is HIV antibody positive will also remain positive for the virus when tested by PCR. Most viral testing is done by PCR or other DNA/RNA amplification methods. Amplification is needed when the sample source contains small numbers of viral copies. Certain viruses such as hepatitis B produce large quantities of viral copies such that the viral load is sufficient to detect via straight antigen testing. Other viruses might produce large quantities of virus, but the number present in a sample source suitable for testing might be small, resulting in the need for amplification. Still other viruses do not replicate rapidly
in vivo and will require amplification for detection.
Most people with healthy immune systems can clear most viruses through production of antibodies and other immune response mechanisms. The very young, very old, and immuno-compromised individuals are at greatest risk of succumbing to any viral (or bacterial) infection. The problem with pandemic inducing viruses is that they are completely different than any strain of any other virus that the human body has seen before, therefore there is no natural immunity by pre-circulating strain-similar antibodies.
Antigen, antibody, and DNA/RNA testing require a test be developed specifically to detect the given virus. Such tests have not yet been developed but would certainly be formulated if large-scale diagnostic testing was needed. Currently the options are to grow the virus in culture or do hemaglutination-inhibition testing, neither of which are done on a large scale.
Is it a hoax? At this point there have been few human cases, certainly nothing to assume that a pandemic is imminent. Can the virus mutate to one that is easily transmitted human-to-human? Sure, but will it? My crystal ball is fuzzy, but I know what it takes to get a new product licensed and it isn't a fast process. Is it worth the money it will cost to develop, test, and produce a vaccine? Possibly not, but by the time we decide we need it there won't be time.