1. Darwin is a human being who had many ideas and said many things throughout his life. You disprove a theory. You don't disprove a human being.
2. Scientific terms must be well-defined, that is "testable" in order to have any meaning. When you say "random"... what exactly do you mean? Does random mean that any outcome is possible (I doubt any scientist would say this)?
3. I don't even think scientists use the word "random mutations" in a scientific way, accept to the popular press to mean "something that can't be predicted". I am trained in Physics rather than evolutionary biology (so you will ask them).
4. I don't know what the term "inspired" means in this context. As a human being, I can look back at previous human beings and think to myself l "wow, that guy was great, I want to be like him.". That is what it means for me to be "inspired".
Are you saying that a "mutation" is able to think to itself as it ponders previous mutations? If you aren't saying that, then what do you mean?
There may be some processes that make some mutations more likely than others. I will let an expert in evolutionary biology speak on that.
As someone trained in science, I will state that it is very important to precisely define your terminology. When you start assigning human cognition to inanimate objects, you are almost certainly failing to do that.