Two remains used in a row. I wonder whether we can or should another word to replace the second

Context:

Sudden Cardiac Death. Despite progress in epidemiology, clinical profiling, and interventions, sudden cardiac death remains a major clinical and public health problem. There remain important unresolved issues that are challenges for future progress. Among these are a better understanding
of the magnitude of the problem and methods of profiling risk for individuals, the etiology and mechanisms of cardiac arrest in individuals with and without previously identified structural heart disease, clinical strategies for primary and secondary prevention of sudden cardiac death, and
further development of community programs for improving cardiac arrest survival in the out-ofhospital environment. Each of these areas of endeavor and potential progress are reviewed and discussed. (J Cardiovasc Electrophysiol, Vol. 12, pp. 369-381, March 2001)