@FBM,
FBM: "As for the 'mind creating matter' position, I suppose that pursuing that in this thread would result in a major derail..."
I would have thought that an adherent of scientism would be logically compelled to admit the mind creating matter position. Perhaps you don't perceive that your position implies it?
What is matter empirically (which is to say phenomenologically)? It's a mental experience you call vision and another you call touch. Those mental experiences are (you say) epiphenomena of neural activities; but there is no reason to suppose that a particular set of "sense organs" and nervous system and brain design cause those mental experiences to bear an objective relation to a putative objective material world which, even if it exists, you can have no direct access to.
In fact, there is good reason to suppose the subjectivity of such brain assembled mental models of the world. The "material world" sensed by a human looks quite different to a squid or a moth; and the science-fiction premise of aliens whose perceptions -- and even they themselves (as far as our perceptions of them are concerned) -- do not exist for us, is not unreasonable, granted the premises of scientism.
You don't have to resort to the extreme of The Matrix to see how perceptions are reality. Just do drugs, or suffer a seizure, or have a neurosurgeon poke around in your brain, or expose yourself to certain kinds of strong electromagnetic fields.
In fact, you don't perceive or measure an objective material world at all: you merely infer it from your perceptual experiences. Scientism, then, is really just a version of Plato's cave.