I just had a terrible lupini experience. See the photo of lupinis in this link to see what I cooked:
http://www.foodsubs.com/Beans.html
I love cooking beans that I have soaked overnight. I assumed lupinis would be the same. After discarding the overnight soaking water and cooking 2 hours they were still firm, the flavor bitter. Water discarded and cooked a further 2 hours, they were softer, and still quite bitter. Nevertheless, we love eating bitter greens and so enjoyed the odd bitter taste, and stewed the beans with a jar of tomato sauce, garlic, and basil, serving it over pasta for dinner tonight. A few hours later, working on the computer, I noticed that I was unable to focus my eyes. I also felt dizzy and hot, nauseous, and was trembling. I went to the washroom, blurrily, and noticed that the light irritated my eyes. Looking in the mirror, my pupils were dilated and unresponsive to the light when I adjusted my distance from the mirror so I could see myself. My cheeks were red, and my mouth was dry. I felt worried and confused, and my words were slurred.
I called my husband, who was feeling off and tired, and who called poison control. I thought I'd eaten lima beans, and they asked if I was mediterranean (I'm english/north european/canadian) and then said my symptoms were wrong but to go to the hospital if they got worse. I felt odd and couldnt' see properly, but it had been hours since dinner, and I didn't think the matter was an emergency. My husband said I must be having a severe allergic reaction, that he felt very tired, and went to bed.
A few hours later now (six), and I have gotten my vision back (3 hours) and can focus my eyes again, although they are sore. I'm not confused anymore, but feel quite nervous at my close call. My mouth is still dry, and I feel residual trembling. There is a knot in my belly that doesn't hurt - the beans are slow to digest. I have identified the beans as lupini beans from the dry bulk store. I have discovered that lupini beans must be soaked for days with many water changes to remove the toxic alkaloids, and that the alkaloids can cause convulsions, dizziness, and other parasympathetic nervous effects. Not to mention that when more than an hour has passed after eating them, stomach pumping may not be any use. If you have seen the film Into the Wild, you will have some idea of how I felt when I read that lupinis can be toxic while my eyes were still blurry. It was terrifying.
The Canadian government has made quite a good food safety website about plant toxins and avoiding them in food prep. Simple food safety for lupini beans is under the heading pulses here:
http://www.foodsafetynetwork.ca/aspx/public/publication_detail_global.aspx?languageid=1&contenttypeid=5&id=83
To explain toxicity (around p17) and dosing while eating lupini as a mediterranean snack, check out this toxicity report by the Australian government here - high doses can kill rats and livestock, humans are more sensitive than rodents, and they are not sure what the dose is if you don't prepare the beans as mediterranean cultures do with much soaking...
www.foodstandards.gov.au/_srcfiles/TR3.pdf
I'm sure I just ate many times the mediterranean snack dose of lupini alkaloids - my dinner was a large bowl of these beans on pasta in sauce, soaked in three scanty pots of water! I'm about 170 lbs and 5'7", and ate about 1 cup of lupini beans over about 1.5 cups of pasta, with about 1/2 cup of garlicky tomato sauce. We cooked the sauce in a seasoned iron pan for hours. Maybe a scientist out there can tell me whether tomato acids, lupini alkaloid, and trace iron from the pan make a new type of toxin. When I give blood, iron is no problem.
Lupini beans MUST be soaked for days in many changes of water to prevent anticholinergic toxicity. My symptoms are classic. I guess they are rarely reported because mediterranean people who would make them from scratch know what to do to eat them safely, and everyone else won't make them or eat them often because they are troublesome, bitter tasting, and tough. Then there are curious people like me who just like to cook and are fond of bitter greens and garlic... Dinner was tasty! Too bad I'll have to throw it out because it made me so ill that the bitterness is obviously a toxic dose of alkaloids for someone my size!! Yes, you should throw out the cooking water and never cook these in soup! Next time, I'll soak them in ten changes of water or more over seven days as those in the know above suggest, and stay healthy. Today was May 26, 2009.