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Norm = threshold?

 
 
Reply Wed 12 Oct, 2011 07:36 pm
A highly accurate explanation is required.
Thanks in anticipation.


Context:
Faced with these daunting therapeutic challenges, physicians in some countries have had to resort to antibiotics with unfavourable toxicity profiles and imited pharmacodynamic guidance (eg, colistin) 16, as well as unconventional combinations of antibiotics that have not been investigated properly. Old ideas are being resurrected, such as the use of lytic bacteriophages, but with little evidence of clinical effectiveness. New approaches, such as defensins, targeted monoclonal antibodies, and agents designed to interrupt mechanisms of pathogenesis (eg, toll-like receptors, quorum sensing) have yet to fulfill their therapeutic potential.

Essentially, even as we are forced to revisit treatments that are more than 30 years old while waiting desperately for new research to bear fruit, we sense a pervasive belief in the scientific community that increasing resistance is the new norm. This is a misleading and costly attitude, both in human and economic terms.

The complete context (legal link for open source):

http://thelancet.cn/dnn1201/lancetcncampaignarticle.pdf
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Type: Question • Score: 1 • Views: 451 • Replies: 9
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JTT
 
  1  
Reply Wed 12 Oct, 2011 07:39 pm
@oristarA,
Norm = threshold?

It could hold such a meaning, but here I'd say that it just means the new normal situation, Ori.
oristarA
 
  1  
Reply Wed 12 Oct, 2011 08:37 pm
@JTT,
JTT wrote:

Norm = threshold?

It could hold such a meaning, but here I'd say that it just means the new normal situation, Ori.


Acceptable.
Yours is better.

Please give me the exact definition of the "situation."
0 Replies
 
JTT
 
  1  
Reply Wed 12 Oct, 2011 09:52 pm
@oristarA,
Quote:
Please give me the exact definition of the "situation."


"We", from the sense we get from the scientific community, is that increasing resistance is the new normal situation.
oristarA
 
  1  
Reply Wed 12 Oct, 2011 11:56 pm
@JTT,
JTT wrote:

Quote:
Please give me the exact definition of the "situation."


"We", from the sense we get from the scientific community, is that increasing resistance is the new normal situation.


Is the Cambridge definition fitting here?
Situation:
the set of things that are happening and the conditions that exist at a particular time and place
0 Replies
 
fresco
 
  1  
Reply Thu 13 Oct, 2011 12:16 am
@oristarA,
The old norm (expectancy of effective treatment)) was that antibiotic X will work against bacteria Y.
The new norm (expectancy of failure) is that Y will be resistant to X. This has lead to unwise (scientifically or ethically questionable) alternative methods.

norm= general expectancy with respect to treatment.
oristarA
 
  1  
Reply Thu 13 Oct, 2011 03:11 am
@fresco,
fresco wrote:

The old norm (expectancy of effective treatment)) was that antibiotic X will work against bacteria Y.
The new norm (expectancy of failure) is that Y will be resistant to X. This has lead to unwise (scientifically or ethically questionable) alternative methods.

norm= general expectancy with respect to treatment.


The sentences in green color are cool, easy to understand.
The bold black gave me a headache (could it be replaced with another word?).
fresco
 
  1  
Reply Thu 13 Oct, 2011 07:23 am
@oristarA,
Sorry about your headache !
Norm =contextual average beliefs and behaviour.
i.e. What is accepted as "normal".
oristarA
 
  1  
Reply Thu 13 Oct, 2011 08:12 am
@fresco,
fresco wrote:

Sorry about your headache !
Norm =contextual average beliefs and behaviour.
i.e. What is accepted as "normal".

Thanks.
The same as JTT has said?
fresco
 
  1  
Reply Thu 13 Oct, 2011 10:01 am
@oristarA,
Yes. the norm has shifted.
0 Replies
 
 

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