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Thu 20 Jan, 2011 04:28 am
Context:
By overlaying those maps with their own maps of RNA production, the scientists were able to observe for the first time that polymerase comes in direct contact with the histone proteins during the transcription process, while also seeing how the nucleosomes acted as a speed bump for the polymerase enzyme as it moved along the genome transcribing DNA into RNA. In addition, the research showed that the organization of histone marks controlled whether "junk RNA" was produced from a given region of DNA.
It equals the polymeraze enzyme. A speed bump is a raised strip of pavement on a street which is intended to make drivers slow down when driving on that street--hitting a speed bump at high speed will cause the car to bounce, and will shake up the driver.
So, the author is saying that the nucleosomes acted to slow down the reactions of the polymeraze enzyme.
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