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might increase the potential for autoimmunity = ?

 
 
Reply Fri 26 Nov, 2010 11:36 pm

might increase the potential for autoimmunity = might increase the possibility for suffering from autoimmune diseases?


Context:

Autoimmunity in antibody deficiency syndromes actually features a broader B cell repertoire and lymphoid hyperplasia, implicating the germinal center as a critical location for in the development of autoimmunity (Mel Berger, CSL Behring and Case Western Reserve University, Cleveland, OH). While in general a diverse repertoire is desired, it has to be the right kind of diversity. Since differentiated plasma cells do not express CD20 and would not be depleted by it, it is now clear that autoantibodies might also be made by immature or mature B cells [24]. Therefore, genetically based defects in the transition from B cell to plasma cell might increase the potential for autoimmunity.
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Type: Question • Score: 1 • Views: 375 • Replies: 2
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JPB
 
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Reply Sat 27 Nov, 2010 10:20 am
@oristarA,
correct again.
oristarA
 
  1  
Reply Sat 27 Nov, 2010 11:14 pm
@JPB,
Thanks.

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