Reply
Wed 24 Nov, 2010 12:17 am
Context:
Thus ALPS has been classified into four distinct types: ALPS 0 (deficiency of Fas caused by homozygous null mutations); ALPS Ia (heterozygous Fas gene mutation); ALPS Ib (heterozygous Fas ligand gene mutation); ALPS IIa (caspase-10 gene mutation); ALPS IIb (caspase-8 gene mutation); and ALPS III (mild clinical features, no mutation identified).
You need someone with specialized knowledge to answer this, or you need to provide more context. Read the portions of the text which precede this passage to see if the text tells you what Fas means.
Fas is Factor of apoptosis stimulus..
(Inducing cells death).
@oristarA,
That's the context I replied to...
@Francis,
In the column of "Gene", it says "fas" is the gene CD95
@oristarA,
It's not exactly that, Ori, CD95 is a particular type of gene within the Fas domain.
Other than a translator, are you skilled in immunology?
Look here:
Fas receptor
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