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Fri 5 Nov, 2010 01:02 am
"the wrong cells are marked for elimination" = "the innocent cells are marked for elimination?"
Or:
"the wrong cells are marked for elimination" = "the normal cells are marked wrongly for elimination?"
Context:
Perforin is also the culprit when the wrong cells are marked for elimination, either in autoimmune disease conditions, such as early onset diabetes, or in tissue rejection following bone marrow transplantation. So the researchers are now investigating ways to boost perforin for more effective cancer protection and therapy for acute diseases such as cerebral malaria. And with the help of a £600K grant from the Wellcome Trust they are working on potential inhibitors to suppress perforin and counter tissue rejection.
I don't understand what it is that you don't understand. Cells are not "innocent" or "guilty," so one can eliminate that right away. Since the article states that perforin is useful as a cancer fighting agent, then, yes, i suppose it would re reasonable to say that normal cells are targeted. But what i don't under stand is why you want to paraphrase this usage. The wrong cells simply means cells which should not be eliminated. Let's hope someone else can give you a better answer.
@oristarA,
Quote:"the wrong cells are marked for elimination" = "the normal cells are marked wrongly for elimination?"
That seems to me to be correct.
@oristarA,
Right, "the normal cells are marked wrongly for elimination". Keep in mind what perforin does. It allows T-cells to punch holes in other cells that it (the T cell) thinks should be destroyed. Usually, this is a good thing and it's exactly how we want our immune system to behave. Sometimes, such as in the case of autoimmune disease, the body turns on itself (auto) and tries to destroy (make us immune to) our own healthy cells.
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