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Sat 16 Oct, 2010 09:13 am
Barrier = blocking?
Can you understand why it blocks the infectious genes of the virus itself?
Context:
The Gag molecule is a microscopic gymnast. At different stages during HIV assembly, the protein twists itself into several different shapes inside a host cell. One shape, or conformation, helps it to drag a piece of HIV genetic material toward the cell membrane, where the viral particles grow. Gag's opposite end becomes anchored there, stretching the protein into a rod-like conformation that eventually helps form a barrier surrounding the infectious genes in the finished virus. But while scientists have been aware for years that Gag appears to play several roles in HIV assembly, the specifics have remained mysterious.
@oristarA,
If I did understand, Ori, I could be a famous scientist who had become aware of the several roles Gag plays in HIV assembly.