@fansy,
												Early on when my wife and I were dating, as a joke we defined a significant change as 3%.  Anything less than that wasn't worth mentioning.  In your case, it depends on how much something regularly changes.  In this case, if stocks routinely move up and down 5%, then 5% is not significant.  10% is probably a good number in this case.  If you are talking about the birth rate in a country where the number is usually pretty stable, then a 3% move would be very significant.