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This = Arpc 1b?

 
 
Reply Thu 29 Jul, 2010 08:58 am

Context:

Lead authors Poonam R. Molli, Ph.D., ex-postdoctoral fellow, and Da-Qiang Li, M.D., assistant research professor, from GW's Department of Biochemistry and Molecular Biology, have identified a protein, Arpc 1b, that serves as both an activator as well as a substrate for Aurora A, an enzyme which plays a central role in cellular reproduction in normal cells but is overexpressed in several cancers. This represents perhaps the earliest step in mitosis and serves as the missing link regarding the role this protein plays in starting the cell cycle and what keeps the process in balance. The authors discovered that Arpc1b also exists as a stand alone protein and believe that it might also play an independent role outside its established contribution to actin machinery.

http://www.sciencedaily.com/releases/2010/07/100722142626.htm
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Type: Question • Score: 1 • Views: 763 • Replies: 5
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PUNKEY
 
  1  
Reply Thu 29 Jul, 2010 07:37 pm
this = identification of the protein
contrex
 
  1  
Reply Fri 30 Jul, 2010 12:38 am
@PUNKEY,
PUNKEY wrote:

this = identification of the protein



I don't agree. "Identification" cannot be "the first step in mitosis".

The part in red below could have been in parentheses...

a protein, Arpc 1b , that serves as both an activator as well as a substrate for Aurora A, an enzyme which plays a central role in cellular reproduction in normal cells but is overexpressed in several cancers. This represents perhaps the earliest step in mitosis
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PUNKEY
 
  1  
Reply Fri 30 Jul, 2010 05:12 am
OK:
authors / have identified / protein

You say:
This (protein) represents / step in mitosis

I say:
This (discovery of the protein) / represents / step
0 Replies
 
PUNKEY
 
  1  
Reply Fri 30 Jul, 2010 05:13 am
Mitosis is the scientific term for nuclear cell division, where the nucleus of the cell divides, resulting in two sets of identical chromosomes
0 Replies
 
dadpad
 
  1  
Reply Fri 30 Jul, 2010 08:56 am
This.... serves as the missing link regarding the role this protein (Arpc1b) plays....

The identification of Arpbc1b serves as the missing link regarding the role this protien plays....
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