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It = receptor?

 
 
Reply Mon 3 May, 2010 06:29 pm


Context:

The work focused on cancerous cells of Hodgkin's lymphoma (the Hodgkin-/Reed Sternberg cells) that originate from white blood cells (antibody-producing B cells). Unusually, this type of lymphoma cell does not contain a so-called 'growth factor receptor' that normally controls the growth of other B-cells.

They found that the lymphoma cells' growth was dependent on a receptor that normally regulates the growth of other immune cells, but it is not usually found in B-cells. However in this case, the Hodgkin-/Reed Sternberg cells 'hijacked' this receptor for their own purposes by activating some of the 'junk DNA'. In fact the lymphoma cells activated hundreds, if not thousands, of LTRs all over the genome, not just one.
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Type: Question • Score: 0 • Views: 546 • Replies: 2
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JTT
 
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Reply Tue 4 May, 2010 02:00 pm
@oristarA,
I'd say that you nailed it, Ori.
oristarA
 
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Reply Tue 4 May, 2010 05:03 pm
@JTT,
Thanks
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