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flipped?

 
 
Reply Tue 23 Mar, 2010 05:44 am
flipped = ?

URL: http://able2know.org/post/ask/english/

Context:

This detail led them to conclude that inherited non-coding DNA sequences " not mutations in genes " may drive the lion's share of differences in where transcription factors attach.

The changes in non-coding DNA that lead to these differences include single-letter changes peppered across the genome as well as structural changes to the genome, in which large chunks of DNA are deleted, duplicated or flipped. Rare deletions of this kind have previously been linked to autism, schizophrenia and obesity.
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Type: Question • Score: 0 • Views: 756 • Replies: 4
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Setanta
 
  2  
Reply Tue 23 Mar, 2010 06:01 am
You're going to need an expert opinion on this one to explain what a scientist means when they say "flipped" in reference to DNA. I advise that you start a new thread, with this information, and entitle it: "What does DNA flipped mean?" This thread title is not necessarily going to attract the attention of someone who knows enough to give you a good answer.
oristarA
 
  1  
Reply Tue 23 Mar, 2010 06:09 am
@Setanta,
Thanks.
0 Replies
 
parados
 
  1  
Reply Tue 23 Mar, 2010 08:00 am
@oristarA,
This may explain it for you:
Quote:
They found a long, 900,000-unit stretch of DNA that didn't correspond to the pattern in the standard human genome: The section was inverted, flipped in the opposite direction.


http://search.japantimes.co.jp/cgi-bin/fe20050210rh.html
oristarA
 
  1  
Reply Tue 23 Mar, 2010 08:57 pm
@parados,
Thank you Parados.
0 Replies
 
 

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