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a large, well-characterized longitudinal clinical cohort ?

 
 
Reply Tue 9 Mar, 2010 10:10 pm

a large, well-characterized longitudinal clinical cohort = a group comprised of many different level physicians ?

Context:

Asked by Medscape Neurology to comment on this study, Dr. Atri said, “I think this is an important study with several exceptional strengths, including utilization of a large, well-characterized longitudinal clinical cohort with useful measure and endpoints and analysis using sophisticated methods guided by good clinical and scientific knowledge from a leader in the field who has an uncommon perspective and expertise, working at the interface of clinical care and clinical trials and utilizing quantitative methodology to address important questions with great practical implications that, thus far, have been mostly neglected, overlooked, and/or underappreciated.”


More context, click:
http://www.medscape.com/viewarticle/718013?src=smo

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Type: Question • Score: 0 • Views: 1,215 • Replies: 7
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DrewDad
 
  1  
Reply Tue 9 Mar, 2010 10:14 pm
Cohort is a group of people.

Clinical cohort is a group of people involved in a medical study, or who meet certain clinical measures.

Longitudinal means that it is a study conducted by following a population over time.

Well-characterized means that the group of people meets the criteria of the study very well.

Large means that there are lots of people in the study.
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oristarA
 
  1  
Reply Tue 9 Mar, 2010 10:19 pm
Thank you.

Cohort includes both researchers and their subjects? What is "endpoints'?
DrewDad
 
  1  
Reply Tue 9 Mar, 2010 10:28 pm
@oristarA,
Cohort is just the people in the study.

DrewDad
 
  1  
Reply Tue 9 Mar, 2010 10:29 pm
@oristarA,
http://en.wikipedia.org/wiki/Clinical_endpoint

Quote:
In a clinical research trial, a clinical endpoint refers to occurrence of a disease, symptom, sign or laboratory abnormality that constitutes one of the target outcomes of the trial.
oristarA
 
  1  
Reply Tue 9 Mar, 2010 10:31 pm
@DrewDad,
Thank you DD.

Who would like to tell what is "endpoint"?
0 Replies
 
oristarA
 
  1  
Reply Wed 10 Mar, 2010 09:06 am
@DrewDad,
Oh my God, you've posted the answer before I posted the second question again.
Thank you DD.
DrewDad
 
  1  
Reply Wed 10 Mar, 2010 09:45 am
@oristarA,
Happy to help. You did ask about "endpoints", though, so I'm not psychic.
0 Replies
 
 

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