By road trip, do you mean overnight? In other words, how far is she going, and where will she be driving? Will she be driving on interstates along the east coast Washington to NYC corridor (or anyplace comparable, for example)? If so, I'd have to say no.
I've been driving for thirty years and the last time I drove on 95 through Washington, I almost got run into a concrete abutment by a truck driver who refused to let me merge.
On the other hand, if you guys live out in west Texas and the roads are straight and uncrowded, that'd be different.
Maybe you could go with her and share driving duties.