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odds ratio, 1.50

 
 
Reply Tue 26 May, 2020 05:59 am
Would you like to explain "odds ratio, 1.50" in this case? It seems to mean that at day 15, remdesivir patients are much better than placebo patients. Just a guess here.

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Discussion
Preliminary results of this trial suggest that a 10-day course of remdesivir was superior to placebo in the treatment of hospitalized patients with Covid-19. This benefit was seen in the number of days to recovery (median, 11 days, as compared with 15; rate ratio for recovery, 1.32 [95% CI, 1.12 to 1.55]) and in recovery according to the ordinal scale score at day 15 (odds ratio, 1.50; 95% CI, 1.18 to 1.91). Even though the trial was ongoing, the data and safety monitoring board made the recommendation to unblind the results to the trial team members from the NIAID, who subsequently decided to make the results public. Given the strength of the results about remdesivir, these findings were deemed to be of immediate importance for the care of patients still participating in the trial as well as for those outside the trial who might benefit from treatment with remdesivir.

Source: New England Journal of Medicine
https://www.nejm.org/doi/full/10.1056/NEJMoa2007764?query=featured_home
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Type: Question • Score: 0 • Views: 619 • Replies: 3
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mark noble
 
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Reply Wed 27 May, 2020 06:05 am
@oristarA,
When was your last flu-vaccine, Please?

Have a Lovely Day
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maxdancona
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Reply Wed 27 May, 2020 07:58 am
@oristarA,
The odds ratio is the ratio of the rate of success in the treatment group compared to rate of success in the placebo group.

In this case it means that the people in the treatment group (i.e. those that received the antiviral) showed a 50% greater chance of recovery at day 15 than the people in the placebo group.
oristarA
 
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Reply Thu 28 May, 2020 12:11 am
@maxdancona,
Thanks.
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