According to the "Sperling Stress Index" which is comprised of nine different factors associated with stress: unemployment rate, divorce rate, commute time, violent and property crime rates, suicide rate, alcohol consumption, self-reported "poor mental health", and number of cloudy days, the following are the most stressful cities:
Tacoma, WA - Highest divorce rates in the country and one of the highest unemployment rates. It's cloudy much of the time, and the suicide and property crime rates are high.
Miami, FL - Highest violent crime rate in the study and one of the highest property crime rates. Long commute time, a high unemployment rate, and a high rate of divorce.
New Orleans - A high violent crime rate and a high unemployment rate. There's also a significant number of suicides and divorces.
Las Vegas, NV - Highest suicide and divorce rates in the study, and a great deal of alcohol use. Residents of Las Vegas have a great number of days experiencing poor mental health.
New York, NY - Longest commute in the country, the hustle and bustle can really stress people out. Unemployment is high and so is violent crime.
Least Stressful Cities:
Albany-Schenectady-Troy, NY and
Harrisburg-Lebanon-Carlisle, PA - Lowest unemployment rates in the country. In fact, both areas score well in many categories- low divorce rates, short average commute times, a low overall crime rate, and low rates of suicide.
Orange County, CA - Little crime, low unemployment, and a whole lot of sunshine. Suicide rate is one of the lowest.
Nassau-Suffolk, NY - Lowest violent and property crime rates in the country. The divorce and suicide rates are also among the lowest in the country, indicating a safe and stable place to live.
Minneapolis-St. Paul, MN - Low unemployment rate and a low violent crime rate. Suicide rate is low and the stress scores are generally favorable across the board.
For the complete listing
http://www.bestplaces.net/stress/stress_study3.asp
By the way jespah- Boston was way down on the list - number 77 out of 100.