A long time ago, a friend gave me a librium, of which I took half, because I was filled with anxiety about driving back east with my troubled father. Not anxiety - much - re my own driving, but his. Ok, well both, given my own eyes. I didn't know then about my nightblindness - as opposed to anyone else's eyes - but I didn't like to drive at night. Anyway, with the half pill, I could barely lift my arm for hours - but I took that not far out of Los Angeles in daylight, in the passenger seat.
That was my last grasp at anything like that, somewhere in the mid-sixties.
We made it to Ohio. I remember still a whacko storm passing Rolla, Missouri, me driving, night. And a Holiday Inn. That we made it.