@The Pentacle Queen,
"When things get big the rules change."
Simply it became well recognized a century ago by physicists grappling with Newtonian Physics formulas to define how the atom worked. They don't, because of the mass of the particles.
In my field, polymers, the same thing is true, and knowing the critical size of a polymer and whether it acts like its functional group, or whether it becomes polymeric "stuff" has helped me save more than one fiber spinning plant and millions of dollars.
But more importantly, in life, recognizing that as things get bigger and more complicated one might be wrong in using the same ways of looking at them as one does when things were not so big or complicated.