Inauguration Day Speech

"... A man who's father who wouldn't be served in a local restaurant a little less than 60 years ago stands before you to take oath of office."
-Barack Obama
That's like so profound. If we could make that much progress as a nation since back in those days, we have limitless possibilities of how far we could go in the future. His speech was addressed as much to the world as to America and was not, "I'm gonna do xyz," but based on values, which is really all it takes to achieve much of anything.
I knew instinctively when I voted for him that I won't ever regret a minute of it.
Some others:
"Ask not what your country could do for you, but what you could do for your country."
-JFK inauguration speech, 1961

"The only thing to fear is fear itself."
-FDR inauguration speech, 1933