0
   

Who Should MDs Let Die in a Pandemic? Report Offers Answers

 
 
JTT
 
  1  
Reply Sun 25 May, 2008 01:35 pm
Finn dAbuzz wrote:
JTT wrote:
I'm no doctor/scientist but I think that a new bug that is able to create a pandemic is going to worry much about a list. By its nature, it'll get those, strong or weak, that don't have the necessary stuff inside to fight it.

It's gonna get a lot of us, no doubt, in more ways than our health. Just imagine for a moment how it's going to affect the economy.

My grandpa nursed a lot of his family thru the 1918 outbreak. He was the only one who didn't get sick. and now that I think about it caused the death of any of my family back then. That seems odd, given how bad it was. More research needed.


The original question assumes that there is something doctors can do to either cure or increase the chance of survival for a given patient.

If nothing can be done for anyone, then of course each individuals natural immune system will determine his or her fate.


Admittedly, that was the question, Finn. Is there anything that can be done in the short term, save for palliative care, for these new strains that will inevitably cause a pandemic?

How quickly can shots be developed and how long does it take for those to be effective after an injection? Currently, shots are given before the flu season, are they not? Does this mean that there is a considerable lag time before immunity is boosted to an effective level?
0 Replies
 
hamburger
 
  1  
Reply Sun 25 May, 2008 02:59 pm
the complexities of planning for a pandemic/disaster :

Hospital Disaster Preparedness in the United States:
New issues, New Challenges


from the report :

Quote:
The Canadian experience with SARS provides some insight into management during a biological disaster. Ontario Ministry of Health Guidelines to manage and mitigate the outbreak commented specifically on adequate hospital staffing [ 7 ]. The Ontario Health Coalition report submitted to the SARS commission specifically noted inadequate hospital capacity and understaffed facilities [ 8 ]. The SARS epidemic resulted in significant psychological stress for hospital staff, as noted by a survey of the hospital staff of a tertiary care facility [ 9 ]. Two thirds of respondents expressed concern regarding their own or their family's health and well-being. While 29% of staff overall met criteria for probable emotional distress, the rate amongst nurses was 45%. The four factors which most correlated with degree of concern for family and personal well-being were perception of a greater risk of death from SARS, living in a household with children, personal or family lifestyle affected by SARS outbreak, and most interestingly, being treated differently by individuals simply because of working in a hospital.


you might want to keep in mind that the SARS outbreak did not spread beyond a small group of patients and medical personnel in toronto , yet it caused widespread anxiety . it had a wideranging impact upon the economy of toronto and the whole province of ontario :
international conferences cancelled , downturn in number of foreign visitors to ontario - especially toronto - at a cost of millions of dollars .

a true pandemic would simply devastate the economy of the world .

the problem of preparing for a pandemic can probably be summed up in one word : MONEY !
who wants to see taxdollars spent on something that might never happen ?
the money for such preparedness would have to come out of taxpayers pockets - who would probably prefer to buy an i-pod , rent a cellphone , buy a new computer , take a nice vacation ... and the list goes on .
0 Replies
 
Chumly
 
  1  
Reply Sun 25 May, 2008 03:20 pm
The problem of preparing for a pandemic can probably be summed up in one concept: A globally needless excess of population in unhealthily close quarters!
0 Replies
 
dlowan
 
  1  
Reply Sun 25 May, 2008 03:31 pm
JTT wrote:
dlowan wrote:
JTT wrote:
dlowan wrote:
I would imagine many of us will cark it at home.


I've never heard that one, dlowan. Interesting. Is it solely Australian?



Not at all.


Or do you mean "cark it"? Don't know where that comes from.



Yup, I meant 'cark it', dlowan. It seems that you've used it as a synonym of 'die'. Can it be used in a passive sense like 'kill' is, as in,

They were carked by the tornado/bird flu.



Not so far. You could start a trend, though. :wink:




Finn dAbuzz wrote:
JTT wrote:
I'm no doctor/scientist but I think that a new bug that is able to create a pandemic is going to worry much about a list. By its nature, it'll get those, strong or weak, that don't have the necessary stuff inside to fight it.

It's gonna get a lot of us, no doubt, in more ways than our health. Just imagine for a moment how it's going to affect the economy.

My grandpa nursed a lot of his family thru the 1918 outbreak. He was the only one who didn't get sick. and now that I think about it caused the death of any of my family back then. That seems odd, given how bad it was. More research needed.


The original question assumes that there is something doctors can do to either cure or increase the chance of survival for a given patient.

If nothing can be done for anyone, then of course each individuals natural immune system will determine his or her fate.




Tamiflu, the drug countries are being advised to stockpile, is something bird flu in humans is already showing signs of developing resistance to.

Countries are now being advised to stockpile TWO anti-viral drugs. Only richer countries will be able to do so.

A vaccine for the strain which finally makes it possible for human to human infection will, by definition, be a new strain, and the vaccine will have to be developed AFTER the epidemic begins.

I assume that life-support measures like breathing support, intravenous fluids, temperature control etc. will have some benefit to those fighting the disease, as will anti-viral drugs for some people.
0 Replies
 
hamburger
 
  1  
Reply Sun 25 May, 2008 05:32 pm
dlowan wrote :

Quote:
I assume that life-support measures like breathing support, intravenous fluids, temperature control etc. will have some benefit to those fighting the disease, as will anti-viral drugs for some people.


as the medical community in toronto found out when there was a SARS outbreak in 2003 , doctors and nurses were at a loss to know what exactly the right response should be to combat and contain the outbreak .

to cite just one example from a lenghty report isued after the sars outbreak . this section of the report deals with what mask would give adequate protection .

Quote:


as you can see , even just finding the right mask was no easy task !

eventually it was determined that full body suits should be worn by those dealing directly with the patients - but there are only a limited number of those suits available since they are quite expensive (which brings us back to square one : MONEY !) .




you can find the full report at this website :

SARS REPORT

finally , i should mention that numerous lawsuits were launched - mainly by nurses and patients that had become infected with SARS .

Quote:
SARS lawsuits against Ontario get the go-ahead
Last Updated: Tuesday, August 23, 2005 | 7:18 PM ET
CBC News
An Ontario judge ruled Tuesday that two lawsuits launched over Ontario's handling of the SARS crisis two years ago can proceed.

Both lawsuits charge that the government put the province's economic interests ahead of the safety of its nurses.

One suit is a $600 million class action by Andrea Williams, a nurse who became infected with SARS on the verge of a second outbreak in May 2003. Williams was exposed to SARS while undergoing a surgical procedure at North York General Hospital in Toronto.

The other is a $12 million suit brought by the family of nurse Nelia Laroza, who died in June. Laroza was an orthopedic nurse at the same hospital.

Both nurses became infected during a second wave of the disease.

Ontario Superior Court Justice Maurice Cullity issued separate rulings Tuesday allowing both suits to go ahead.

By mid-August 2003, 44 people in the Toronto area had died of SARS.
0 Replies
 
Finn dAbuzz
 
  1  
Reply Sun 25 May, 2008 05:37 pm
JTT wrote:
Finn dAbuzz wrote:
JTT wrote:
I'm no doctor/scientist but I think that a new bug that is able to create a pandemic is going to worry much about a list. By its nature, it'll get those, strong or weak, that don't have the necessary stuff inside to fight it.

It's gonna get a lot of us, no doubt, in more ways than our health. Just imagine for a moment how it's going to affect the economy.

My grandpa nursed a lot of his family thru the 1918 outbreak. He was the only one who didn't get sick. and now that I think about it caused the death of any of my family back then. That seems odd, given how bad it was. More research needed.


The original question assumes that there is something doctors can do to either cure or increase the chance of survival for a given patient.

If nothing can be done for anyone, then of course each individuals natural immune system will determine his or her fate.


Admittedly, that was the question, Finn. Is there anything that can be done in the short term, save for palliative care, for these new strains that will inevitably cause a pandemic?

How quickly can shots be developed and how long does it take for those to be effective after an injection? Currently, shots are given before the flu season, are they not? Does this mean that there is a considerable lag time before immunity is boosted to an effective level?


Avian flu is the current source of pandemic related fears, but of course a pandemic in the near of mid-term future would not be limited to this virus as a cause.

There is already an avian flu vaccine and it has been stockpiled in Europe and the US.

It is unlikely however that the disease can spread to epidemic proportions in either place if the disease continues, for humans, to require contact with infected fowl. As dlowan suggests, the current strain must mutate before it can be transmitted between humans, however while the life cycle of a virus allow for relatively rapid mutations, the mutations will remain random, and so there is, from a probabilty standpoint, the same chance for a mutation to be harmful to the virus than it is for it to spread between humans. The former mutation is not as likely to take hold as the latter, but the point is that a mutation allowing human to human transmission is by no means inevitable.

It is also not certain that a mutation that enables the virus to pass from human to human will render the current vaccine ineffective, although we would need luck for this to not be the case.

The creation of a viral vaccine is, by no means, assured or we would have a vaccine for HIV, however, as there is already a vaccine for the current strain of avian flu, the chances are reasonably good for a vaccine to be created that would be effective for a mutated version.

Of course there is a fair possibilty that the mutated virus will result in a pandemic (beginning in the Third World) before an effective vaccine can be created which means a large number of people will die.

You're right though that, unless the virus has a 100% mortality rate, prompt, quality medical care should help some victims allow their natural defenses to fight off the virus. The sort of virus that taxes this sort of relatively minimal care (I.e. IVs, vitamins, fever reducers etc) would really be a nightmare.

It is always possible, of course, that a virulent viral strain that defies all attempts at a vaccine will drastically decimate the human population (a la King's "Captain Tripps"), but natural immunities, born of mutation, are bound to be found in a population topping 3 billion, and so extinction is not likely.

I could easily be wrong here but I don't believe there is evidence of any species become extinct solely through disease.

As for those who seems to be suggesting that a highly lethal pandemic is somehow a good and natural response to over-population, I doubt they will be so clinical when they, like your grandfather, watche it exterminate their families.
0 Replies
 
Chumly
 
  1  
Reply Sun 25 May, 2008 06:26 pm
Quote:
Paper No. 10-0
PANZOOTICS, PARSIMONY, AND PALEONTOLOGY: CAN DISEASE CAUSE EXTINCTION?
MACPHEE, Ross D.E., Division of Vertebrate Zoology, American Museum of Nat History, New York, NY 10024, [email protected].

During the late Quaternary, mammalian faunas were affected almost worldwide by an unusual series of extinctions that were highly regionalized and temporally disjunct. Thus, about 11,000 bp in the Americas 130+ species (including mammoths, mastodonts, "ground" sloths, sabertoothed cats, and many others) disappeared very suddenly, perhaps in the space of 400 yr. Similar but smaller losses occurred in Australia/New Guinea ~ 50,000 bp, in the West Indies ~ 5000 bp, and in Madagascar ~ 1000 bp. These extinctions are widely believed to have been anthropogenic in nature, and thus represent the "first" biodiversity crisis forced by our species. But what is the evidence for this conclusion? Overhunting is frequently mentioned as the leading cause, but for several reasons it is highly improbable that primitive peoples could have induced so many species losses in this way. Climate change is even more unlikely. As an alternative, I propose that most features of late Quaternary extinctions can be explained by inferring that the principal agency of loss was infectious diseases introduced into immunologically naive populations by colonizing humans or their commensals/synanthropics. The "hyperdisease hypothesis" potentially (1) explains differential losses in K-selected vs. r-selected taxa (both young and old animals highly susceptible to disease, causing catastrophic depression in rate of natural increase in larger taxa); (2) requires no ad hoc explanations for the absence of mass kill sites in affected areas (mass kill sites absent because losses attributable to human hunting were usually negligible); and (3) accounts for pattern change in the character of anthropogenic extinction after first-contact losses. Recent successes in utilizing "ancient DNA" techniques for recovering evidence of viruses in fossils will be discussed.

GSA Annual Meeting, November 5-8, 2001
General Information for this Meeting
Session No. 10
The Emerging Discipline of Medical Geology
Hynes Convention Center: Ballroom B
8:00 AM-12:00 PM, Monday, November 5, 2001


--------------------------------------------------------------------------------
© Copyright 2001 The Geological Society of America (GSA), all rights reserved. Permission is hereby granted to the author(s) of this abstract to reproduce and distribute it freely, for noncommercial purposes. Permission is hereby granted to any individual scientist to download a single copy of this electronic file and reproduce up to 20 paper copies for noncommercial purposes advancing science and education, including classroom use, providing all reproductions include the complete content shown here, including the author information. All other forms of reproduction and/or transmittal are prohibited without written permission from GSA Copyright Permissions.


http://gsa.confex.com/gsa/2001AM/finalprogram/abstract_19794.htm
0 Replies
 
Chumly
 
  1  
Reply Sun 25 May, 2008 06:29 pm
Quote:
An international campaign has been launched to help save the world's amphibians from extinction.

Amphibians are under threat

Amphibians have thrived for hundreds of millions of years but as many as half of all species could perish unless a solution is found. The spread of the parasitic fungus amphibian chytrid, which has proved deadly for hundreds of amphibian species, may have been made worse by the effects of global warming. The disease has so far proved unstoppable in the wild and can kill 80 per cent of native amphibians within months once it has taken hold.

Amphibians are important as an 'indicator species' - similar to canaries in a coal mine - who serve as a warning when there is something wrong with the environment. Now 2008 has been designated Year of the Frog by conservationists to raise awareness of the plight of amphibians and to raise the funds needed for a concerted worldwide effort to save them.

The Amphibian Conservation Action Plan (ACAP) aims to protect the habitat of the amphibians while at the same time finding answers to the environmental problems they face.

The biggest initiative will be an amphibian version of Noah's Ark costing an estimated £30m where the most vulnerable species will be moved into protected areas in zoos, aquariums and other institutions around the world so their future survival can be guaranteed.

advertisementThe ambitious rescue plan is being organised by the IUCN/SSC Conservation Breeding Specialist Group, the IUCN/SSC Amphibian Specialist Group, and the World Association of Zoos and Aquariums (WAZA).

"Widespread extinction of amphibians would be catastrophic," said Jeffrey P. Bonner, chairman of Amphibian Ark and president and CEO of the St. Louis Zoo.

"In addition to their intrinsic value, they offer many benefits and are a critical part of a healthy world. They play an important role in the food web as both predator and prey, eating insects which benefits agriculture and minimizes disease spread. Their skin also has substances that protect them from some microbes and viruses, offering promising medical cures for a variety of human diseases.

The conservation groups hope the captive management plan will buy time for the most endangered species which will eventually be reintroduced back into the wild once the threats they face have been removed.

It is hoped the Year of the Frog campaign will raise awareness of the crisis among media, educators, corporations, philanthropists and governments and will generate the funding needed to make the campaign a success.

Sir David Attenborough, who is patron of the campaign, said, "The global zoo and aquarium community has taken on this challenge with enthusiasm and is providing appropriate facilities and breeding grounds within their institutions. But implementation calls for financial and political support from all parts of the world. Without an immediate and sustained conservation effort to support captive management, hundreds of species of these wonderful creatures could become extinct in our own lifetime."

Amphibians are severely affected by habitat loss, climate change, pollution and pesticides, introduced species, and over-collection for food and pets.

Jörg Junhold, Ph.D., chair of the Amphibian Ark Year of the Frog campaign and director of Zoo Leipzig, said: "It is of utmost importance to raise awareness among national governments, world media, school educators, corporations, philanthropists, and the general public about the fragility of amphibians and the enormous responsibility that each of us has in trying to rescue the amphibians in danger."

"The outcome of the Amphibian Ark project will be that we will have saved hundreds if not thousands of species from extinction. We also will have developed a capacity both within our institutions and globally to continue to provide amphibian species with care and protection when needed, formed a true partnership between offsite and onsite components of conservation, and demonstrated to the world that zoos and aquariums are essential conservation organizations."


http://www.telegraph.co.uk/earth/main.jhtml?xml=/earth/2008/01/01/eafrog101.xml
0 Replies
 
Chumly
 
  1  
Reply Sun 25 May, 2008 06:30 pm
Quote:
We believe this is the first definitive report of an infectious disease causing the extinction of a species.

http://www.google.ca/search?hl=en&sa=X&oi=spell&resnum=0&ct=result&cd=1&q=extinction+disease&spell=1
0 Replies
 
Chumly
 
  1  
Reply Sun 25 May, 2008 06:35 pm
Finn dAbuzz wrote:
As for those who seems to be suggesting that a highly lethal pandemic is somehow a good and natural response to over-population, I doubt they will be so clinical when they, like your grandfather, watche it exterminate their families.
Your specious moralizing does nothing to change the underlying facts that a globally needless excess of population in unhealthily close quarters is an accident waiting to happen. Let alone the fact that your preoccupation with the straw man logical fallacy deflates your assertions to the level of a fart in the wind.
0 Replies
 
dlowan
 
  1  
Reply Sun 25 May, 2008 08:38 pm
hamburger wrote:
dlowan wrote :

Quote:
I assume that life-support measures like breathing support, intravenous fluids, temperature control etc. will have some benefit to those fighting the disease, as will anti-viral drugs for some people.


as the medical community in toronto found out when there was a SARS outbreak in 2003 , doctors and nurses were at a loss to know what exactly the right response should be to combat and contain the outbreak .

to cite just one example from a lenghty report isued after the sars outbreak . this section of the report deals with what mask would give adequate protection .

Quote:


as you can see , even just finding the right mask was no easy task !

eventually it was determined that full body suits should be worn by those dealing directly with the patients - but there are only a limited number of those suits available since they are quite expensive (which brings us back to square one : MONEY !) .




you can find the full report at this website :

SARS REPORT

finally , i should mention that numerous lawsuits were launched - mainly by nurses and patients that had become infected with SARS .

Quote:
SARS lawsuits against Ontario get the go-ahead
Last Updated: Tuesday, August 23, 2005 | 7:18 PM ET
CBC News
An Ontario judge ruled Tuesday that two lawsuits launched over Ontario's handling of the SARS crisis two years ago can proceed.

Both lawsuits charge that the government put the province's economic interests ahead of the safety of its nurses.

One suit is a $600 million class action by Andrea Williams, a nurse who became infected with SARS on the verge of a second outbreak in May 2003. Williams was exposed to SARS while undergoing a surgical procedure at North York General Hospital in Toronto.

The other is a $12 million suit brought by the family of nurse Nelia Laroza, who died in June. Laroza was an orthopedic nurse at the same hospital.

Both nurses became infected during a second wave of the disease.

Ontario Superior Court Justice Maurice Cullity issued separate rulings Tuesday allowing both suits to go ahead.

By mid-August 2003, 44 people in the Toronto area had died of SARS.



Yeah.....I know.


It's obviously hard for us to envision a serious pandemic.


Personally, since taking a good, hard look at the possibility of a bird-flu pandemic, I have decided not to bother about it. I will get the best mask they can think of at work (and, if I remain well, I suspect my job description will change to "feeder, washer, cleaner up of ****, urine, vomit and other unpleasant human exudations, monitorer of drips and such, and general dogsbody" for the duration of the pandemic, followed by trying to help with the trauma after), and I may have some soup and stuff stockpiled, but I think survival will be a matter of luck.


So it goes.
0 Replies
 
Finn dAbuzz
 
  1  
Reply Sun 25 May, 2008 11:04 pm
Chumly wrote:
Finn dAbuzz wrote:
As for those who seems to be suggesting that a highly lethal pandemic is somehow a good and natural response to over-population, I doubt they will be so clinical when they, like your grandfather, watche it exterminate their families.
Your specious moralizing does nothing to change the underlying facts that a globally needless excess of population in unhealthily close quarters is an accident waiting to happen. Let alone the fact that your preoccupation with the straw man logical fallacy deflates your assertions to the level of a fart in the wind.


talk7200 wrote:
With 6 billion people on earth I wouldn't worry about saving people. The over population brings about disease due to waste production and the resulting unsanitary conditions. Scarce resources brings about war, famine, starvation and pandemic diseases. It is natures way of culling excess humans.


Your awfully defensive Chumly old chum. Especially about a fart in the wind. Cool
0 Replies
 
talk72000
 
  1  
Reply Thu 29 May, 2008 10:31 pm
Pandemics could not happen in modern day life as we now have indoor plumbing and rather clean street. The last pandemic in 1918 happened because they were no indoor plumbing. People used to go to outhouses and street drains used to contain urine and faeces.
0 Replies
 
dlowan
 
  1  
Reply Thu 29 May, 2008 11:13 pm
talk72000 wrote:
Pandemics could not happen in modern day life as we now have indoor plumbing and rather clean street. The last pandemic in 1918 happened because they were no indoor plumbing. People used to go to outhouses and street drains used to contain urine and faeces.




Air-borne virus.


Rolling Eyes
0 Replies
 
talk72000
 
  1  
Reply Sun 1 Jun, 2008 10:00 pm
It is the poultry farmers who are at fault. They coop the birds in close quarters in unclean antibiotics. Antibiotics don't work on viruses and when a virus hits the birds they all die and spread the disease thru the air.
0 Replies
 
hamburger
 
  1  
Reply Mon 2 Jun, 2008 09:31 am
keep using the outhouse - a clean outhouse is better than a grimy "inhouse" !

the line forms to the RIGHT !

http://www.gerlecreek.com/documents/outhouse.jpg
0 Replies
 
Foxfyre
 
  1  
Reply Wed 4 Jun, 2008 02:40 pm
Interesting thread. Little time for now. (Bookmarked)
0 Replies
 
 

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