There is something to the "Run it hard from the get-go" approach - it pretty much is the way an aircraft or racing engine is broken in, after a brief period of low-rpm warm-up to get everything to operating temperature. Pretty much the same goes for prime-mover powerplants, such as locomotive or large marine engines. However, the pre-assembly cleaning, and the actual assembly tolerances, of high performance and/or dedicated severe duty commercial engines are more rigorous than those typical of production consumer-service power plants. Also, the maintenance schedule of such engines includes periodic tear-down, inspection, and rebuild proceedures, something not typical of automobiles and light trucks in general service.
The main reason I do a couple short-interval oil-and-filter changes right at the beginning is to ensure any casting debris and/or machining burrs are out of the system. Myth or reality, it works for me - witness hundreds of thousands of miles without major engine repairs; factoring the cost of a few quarts of oil and a couple filters against a heads-off rebuild, with new gaskets, bearings, crank, rods, pistons, rings, wrist pins, timing train, valves, springs, cam, and lifters, I just don't see the upside of finding out whether the break-in pays or not.
Another thought here - unlikely to be of much application in the case of a small pickup or a passenger car, but after a few hours of sustained heavy work, particularly in a dusty environment, I generally do an oil & filter change regardless of mileage. My tractors get serviced on an hours-of-operation schedule, oil change at around 50 hours, oil & filter every second change. The Maule (
* ) gets its oil and filters changed every 60 days or 50 hours of operation, whichever comes first.
And I can't say as I see any cost/benefit advantage to synthetic oil, either. I'm with rog's mechanic on that; use good commercial grade oil, and change it regularly.