Unsure about College

I am a freshman at my University. I chose this college because it’s not too far from home and is the only school in the country that offers my major as an undergrad. So far, college is not what I expected. I am just super unhappy and I wake up and cry. The classes I am taking are super hard and take a lot of effort for me to teach myself since the instructors don’t. I’ve gone to tutors and stuff but it’s better if I learn on my own. It is very hard to reach out to people and I feel like I’m always the initiator and go out of my way and people turn me down most of the time. They say they are busy or with someone else during that time. I am involved in clubs and organizations I just don’t feel completely happy here for some reason. Part of this is because I was super close to my roommate first semester and now we don’t talk. I’m not sure what happened but she just stopped talking to me and we are the same major and have all the same classes but she’ll ignore me when we are with other classmates. I do not have a problem with her but I think her one friend is changing her. One on one she’s fine but whenever she’s with this one particular friend she is rude and ignores me in class. Some of the people in class have reached out to me and asked what’s going on. It makes it difficult to go to class when I know I have to deal with this and it’s honestly defeating. I talked to my other roommate about this and she was sympathetic to me. She’s nice and all but I don’t see her since we are different majors and our schedules never line up. It is hard for me to get close to people and I’ve always struggled with it and we are basically just acquaintances. I see the same people in my class and they are all cliquey and it reminds me so much of high school and they were so rude. Everyday feels the same and the routine is killing me. My mom said that I could just transfer to a closer school where my sibling is at but they don’t offer my major there and I could only do my sophomore year classes and eventually transfer back to this college my junior and senior years. It’s just really exhausting and I feel overwhelmed all the time and I don’t have answers for any of this. I’ve taken career quizzes and spent a lot of time reflecting about what I should do but I feel like I’ve hit the end of the road. I just feel so depressed and I’ve never struggled with it before. I’ve had anxiety and it’s the worst it’s ever been and I’ve had to change to a stronger medication because of it. I’ve missed my periods because of stress and it’s taking a toll on my health. My partner has noticed that I’m not as upbeat as I usually am and tired all the time and not in the mood. I workout everyday and it temporarily helps relieve the stress. Any advice is helpful.