How exciting this must be for you. I have two daughters one just graduating from college this year and the other graduating from high school and will onto college in the fall like you.
Speaking from their experiences – my older daughter is an introvert and a homebody like you. She decided to actually spread her wings and travel over a 10 hour drive to college. It has been her best experience – although still an introvert she opened up more – she did not know anyone at the college she went to. When we visited the campus she just knew this was the one for her.
I think you should go with your instincts. From what I read you seem to like UOR better. As long as the school you choose is strong academically for what you want to pursue – pick the one that “feels” better to you. I would caution you against choosing a school for a friend or friends or even a boyfriend. If your relationship is meant to be it will last. However, because at this time in your life you discover and change a lot, many relationships (whether it be friends or boyfriends) end. I am not saying yours will, but many do. In my daughter’s situation with all the new friends she made at college many had boyfriends – I believe all are no longer together except one couple. Again this does not mean you two will split, just it is a possibility and you would not want to pick one school over another for that reason or for the reason of a friend or friends.
This is your time to start a new chapter and sometimes not knowing anyone is the best way. You will meet people through orientation and other ways. Most schools pull together games, functions, etc for the incoming freshman class to help them make these new bonds.
Also you do not make mention of money! College is a big expense and so you should consider that in as well – meaning if you are deciding by two and one would save in a good amount then I would lean that way especially if med school is in your future. As far as which school is better academically for what you want to do – I would refer you to your guidance counselor they are in the best position for that. Like I said if both are strong academically I would choose the what “feels” good to you – you will not just be taking classes but being part of that community. My daughter actually chose a school that was very good academically for her major and turned down one that was a little stronger academically because she knew this school fit her overall.
And good luck and congratulations – this is such an exciting time for you fully grasp it! As a mom, I am happy for you!