Covid Vaccine Informal Poll and Drinking Society

It wasn't her, it was her mother.

Why we struggle to protect the young from conspiracy theorist parents


The inquest into the death of Paloma Shemirani, the daughter of a British conspiracy theorist, was like something out of a TV show.

As it unfolded, the medical world clashed with "Conspiracyland", with experienced doctors questioned in courtrooms by people who believe in medical disinformation.

Paloma Shemirani, a Cambridge University graduate from East Sussex, died in July last year - seven months after being diagnosed with non-Hodgkin lymphoma. She had been told conventional treatment would give her a high chance of survival, but rejected chemotherapy in favour of alternative methods, like juices and coffee enemas.

Paloma's twin brother Gabriel has long pointed the finger at their mother Kate. He strongly believes that Kate's beliefs were behind Paloma's decision to reject chemotherapy.

On Thursday, coroner Catherine Wood said Paloma was "highly influenced" by her mother's beliefs - as well as others including a family friend and her dad. They all advocated the alternative treatment she used.

"The influence that was brought to bear on Paloma... did contribute more than minimally to her death," the coroner said.

The COVID-19 pandemic, which by early January 2025 has resulted in more than 7 million deaths worldwide, including nearly 170 000 in France, has had a devastating impact on global health, reversing the trend of increasing life expectancy observed over the past decade.1 Vaccination has played a central role in mitigating the impact of the COVID-19 pandemic, saving millions of lives globally.2,3 Several ecological studies have reported a significant correlation between higher COVID-19 vaccination coverage and lower all-cause mortality rates.4-7 While the protective effect of vaccines on COVID-19 mortality is well-established,8 concerns remain about long-term vaccine safety.
[... ... ...]
Conclusions and Relevance: In this national cohort study of 28 million individuals, the results found no increased risk of 4-year all-cause mortality in individuals aged 18 to 59 years vaccinated against COVID-19, further supporting the safety of the mRNA vaccines that are widely used worldwide.

US Secretary of Health and Human Services Robert F. Kennedy Jr. has criticized the German government for criminal proceedings in connection with the corona pandemic and accused it of disregarding the autonomy of patients. For this reason, he sent a letter to German Health Minister Nina Warken on Friday, he announced on the X platform. He incorrectly gave the minister's surname as "Workin".

In a video attached to the post, he said that he had learned that "more than 1000 German doctors and thousands of their patients" were currently being prosecuted and punished because they had granted exemptions from wearing masks and vaccinations against Covid-19 during the coronavirus pandemic. "The reports from Germany show that the government is sidelining patient autonomy and restricting people's ability to act on their own beliefs when making medical decisions."


7.48 pm
Kennedy Jr. criticizes Germany over corona proceedings
US Secretary of Health and Human Services Robert F. Kennedy Jr. has criticized the German government for criminal proceedings in connection with the corona pandemic and accused it of disregarding the autonomy of patients. For this reason, he sent a letter to German Health Minister Nina Warken on Friday, he announced on the X platform. He incorrectly gave the minister's surname as "Workin".

In a video attached to the post, he said that he had learned that "more than 1000 German doctors and thousands of their patients" were currently being prosecuted and punished because they had granted exemptions from wearing masks and vaccinations against Covid-19 during the coronavirus pandemic. "The reports from Germany show that the government is sidelining patient autonomy and restricting people's ability to act on their own beliefs when making medical decisions."

External Content
This content comes from external providers such as YouTube, Tiktok or Facebook. Please enable “Swisscom Third Party Advertising” to view this content.

In Germany, numerous cases have ended up in court in various federal states, involving allegations of falsification of vaccination certificates or false certificates for exemption from the mask requirement, for example. However, it was not clear from his post exactly which reports the US minister relied on for his accusations and, in particular, where he got the figures quoted from.

Kennedy Jr. is considered a particularly controversial figure in US President Donald Trump's cabinet. In recent years, the nephew of former US President John F. Kennedy has frequently cast doubt on vaccinations, spread conspiracy theories and made a name for himself with strident statements.

Abstract
Background
Vaccine-induced immune thrombocytopenia and thrombosis (VITT) is a rare prothrombotic complication that occurs after adenoviral vector–based vaccination against coronavirus disease 2019; in rare cases, it can also occur after natural adenovirus infection. VITT is mediated by platelet-activating antibodies against the highly cationic protein platelet factor 4 (PF4). The underlying inciting antigen trigger and immunopathogenesis remain unknown.

Methods
We used antibody proteomics to determine the amino acid sequences of anti-PF4 antibodies from 21 patients with VITT and sequenced the genes encoding the immunoglobulin light-chain hypervariable region from 100 patients with VITT. To identify an adenoviral trigger, we used the antigen-binding fingerprints of anti-PF4 and anti–adenovirus protein antibodies to identify a shared serum clonotype and subsequently used adenovirus protein peptides and recombinant anti-PF4 VITT antibodies to map the mimicking linear epitope.

Results
Genomic and proteomic profiling of VITT antibodies revealed a shared immunoglobulin light-chain allele, IGLV3-21*02 or *03, harboring a critical somatic hypermutation, K31E. Only antibodies purified against adenoviral core protein VII (pVII) contained anti-PF4 species matching the VITT fingerprint; antibodies against intact virions or other adenoviral proteins did not. Cross-reactive IgGs were mapped to a basic linear epitope on pVII. A pathogenic anti-PF4 VITT antibody, back-mutated to germline (K31), lost its prothrombotic activity in vitro and in vivo and preferentially bound pVII, a finding that directly supported the role of the hypermutation in the antigenic shift from adenovirus pVII to PF4.

Conclusions
The results of our study indicate that VITT occurs when, in persons with immunoglobulin light-chain allele IGLV3-21*02 or *03, a specific somatic hypermutation develops that affects antibodies that recognize a specific epitope on the adenoviral core protein pVII, which results in misdirection of antibody targeting toward PF4. (Funded by Deutsche Forschungsgemeinschaft and others; German Clinical Trials Register number, DRKS00025738; EU Post-Authorization Study Register number, EUPAS45098.)