use a 50 amp double breaker in the panel "probably 6-6-6-6 guage SER service entrance cable" (not 100% sure on wire size) for the spa.
use a 20 amp breaker and 12-2 wire for the patio GFCI outlet
I would get an electrician since there are many separate codes for pool areas, and how to wire them. also a different wire setup might come out of the disconnect to the actual spa unit. As long as the spa has lights or buttons with lights you will need a nuetral