Mybe, but extreme hybridization seems to impose limits of viability.
There certainly is a point at which reproduction stops working (sterile offspring). But at every point before that I think there is probably a large benefit to both populations through the increase in variation.
In the case of the Coywolves this type of variation within the population led relatively quickly to a new breed of Canis which fit the available ecosystem. And this particular ecosystem is changing rapidly which is also interesting because the dynamic environment seems to have given rise to a dynamic gene pool which allows the organism(s) to adapt faster which is what they need.