Saw it yesterday. I have some definite mixed feelings. Overall, I liked it. it was a "romp," and the over the top Dracula (I think someone has watched too many Kevin Cline performances) was great. Kate Beckinsale in a corset is always worth watching, and, surprise of surprises, there was even a plot!
And as a huge James Bond fan, the early scenes in the Vatican Labs were quite rewarding.
The bad things: It seemed to have been edited poorly. Cuts were very rough, and it almost seemed like important backstory elements were randomly excised (If, like me, you read theology, you know that the archangel Gabriel sits at the left hand of God, thus explaining who Van Helsing really is. (at least according to most medieval studies on angelology

), however, I'm sure such comments went right over the heads of most of the audience). In addition, I was dissapointed with the ending. Yes, it worked, but damnit...how dare they!?!