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Mon 29 Jul, 2013 03:35 pm
5. Two new drugs have been approved for treating attention deficit hyperactivity disorder (ADHD) in children. Researchers are interested in comparing the length of time that each of these drugs is effective in reducing ADHD behaviours. A sample of 12 children diagnosed with ADHD has been randomly selected and each child has been observed over a period of 24 hours after receiving Drug A. After a week’s time interval, each child is observed over a period of 24 hours after receiving Drug B. The data show the length of time (in hours) after the drug has been administered before symptoms of ADHD recur. Do the data suggest that one drug lasts longer than the other?
Participants Drug A Drug B
1 2.0 3.5
2 3.6 5.7
3 2.6 2.9
4 2.6 2.4
5 7.3 9.9
6 3.4 3.3
7 14.9 16.7
8 6.6 6.0
9 2.3 3.8
10 2.0 4.0
11 6.8 9.1
12 8.5 20.9
a. What statistical test will you use and why?
b. What do you conclude?
@aisha25,
I suggest there is a flaw in your stated procedure. You need to randomize the order of giving A or B first, and the observer should be unaware of the order.
Try the Wilcoxon test for matched pairs. Note that "onset of symptoms" implies a more nebulous judgement (i.e. a non-parametric test) rather than the "interval" data implied by timing (where you might use a parametric test).