@Razzleg,
Yes.
One though I had when posting was that we normally refer to teenagers who cut themselves, for instance, as self-destructive.
Simultaneously, many people hold that destruction of the self is one of the highest ambitions of buddhism. Personally I think that is a misinterpretation of buddhism.
The first form of self-destruction is generally thought of as negative, while the second form is associated with more positive motivations.
But then there is the consideration that those teenagers who go through self-destructive periods, often end up as more reflected adults than those who merely surfed through without ever questioning or doubting themselves.
These are all impressions. The OP is vague because I haven't really defined the subject all that well.