6
   

What does "basket" mean here?

 
 
Reply Fri 23 Nov, 2012 09:12 am

Context:

Dr. Mei suspects that if he could look at the chandelier and basket interneurons in the prefrontal cortex of schizophrenics, he would also find something wrong with their usual role of sensing the need for the inhibitor GABA and supplying it to the pyramidal cells. "In schizophrenia, the baseline of the excitatory neurotransmitter is probably high," he said.

More:

http://www.sciencedaily.com/releases/2009/12/091228163308.htm
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Type: Question • Score: 6 • Views: 970 • Replies: 5
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View best answer, chosen by oristarA
izzythepush
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  2  
Reply Fri 23 Nov, 2012 09:29 am
@oristarA,
This is a science question, not a language question. This is what Wikipedia has to say.

Quote:
Basket cells are inhibitory GABAergic interneurons found in several brain regions: the molecular layer of the cerebellum, the hippocampus, and the cortex.In the cerebellum, they synapse on the cell bodies of Purkinje cells, and are multipolar and stellate, with freely branching dendrites, which are dilated and knotty.
Hippocampus
Hippocampal basket cells target somata and proximal dendrites of pyramidal neurons. Cortical[1] and hippocampal basket cells are parvalbumin-expressing and fast-spiking.

Cortex
In the cortex, basket cells have sparsely branched axons giving off small pericellular, basket-shaped elaborations at several intervals along their length. There are three types of basket cells in the cortex, the small, large and nest type: The axon of a small basket cell arborizes in the vicinity of that same cell's dendritic range. In contrast, large basket cells innervate somata in different cortical columns. The nest basket cells are an intermediate form of the small and large cells, their axons are confined mainly to the same cortical layer as their somata.


So the phrase is basket neuron.

http://en.wikipedia.org/wiki/Basket_cell

McTag
 
  1  
Reply Fri 23 Nov, 2012 09:33 am
@izzythepush,

That's what I was just going to say.
izzythepush
 
  0  
Reply Fri 23 Nov, 2012 12:52 pm
@McTag,
Is that where 'basket case' comes from? Probably not.
0 Replies
 
JTT
 
  1  
Reply Sun 25 Nov, 2012 11:06 am
@izzythepush,
Quote:
This is a science question, not a language question.


You've made the leap from ESL to native speaker, Ori.
0 Replies
 
kentkodiak
 
  1  
Reply Tue 27 Nov, 2012 07:11 pm
@McTag,
me too
0 Replies
 
 

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