What is the maximum safe injection of "Salmonella fluid"?

Studies involving healthy human volunteers required a median dose of 1 million bacteria to produce disease. However, point outbreaks suggest as few as 200 bacteria may produce nontyphoid gastroenteritis.

Mortality/Morbidity

Twenty percent of patients require hospitalization, with an estimated death rate of 0.6%.[15] Infection with drug-resistant nontyphoid Salmonella and Salmonella typhi increase the likelihood of hospitalization and death.[15]

Invasive nontyphoid Salmonella infection occurs in about 5% of cases in Israel[15] and is responsible for 400-600 deaths in the United States each year[5] . Mortality for nontyphoid Salmonell a is reported to be as high as 60% in African patients with HIV.[16] Mycotic abdominal aortic aneurysms are more common in immunocompromised and HIV patients.

Treated typhoid cases have a 2% mortality rate with a 15% relapse rate.[3] A significant number of typhoid patients become chronic asymptomatic carriers and can shed high numbers of bacteria in the stool for a lifetime without obvious symptoms.[16] Depending on the serotype, roughly 1% of adults and 5% of children excrete organisms for greater than a year.[18]

In sepsis, blood pressure drops, resulting in shock. Major organs and body systems, including the kidneys, liver, lungs, and central nervous system, stop working properly.