Question about hypothetical excitation of A-delta-fiber-nociceptors

Reply Sun 30 Oct, 2011 03:05 am

I asked a similar question in the past. I apologize profusely if anyone is annoyed by what seems like a repetitive post.

Let’s say all the A-delta fiber nociceptors supplying the peripheral somatic tactile *afferent* nerves in my body are stimulated by a magical source. They are all stimulated at the same time. The intensity to which they are stimulated [measured by their firing rate or frequency] are all in sync with each other. This intensity of stimulation starts of to small-enough extent that the effects are not noticeable. In a smooth, sine-wave-like manner this intensity gradually increases such that it reaches the maximum possible in 30 minutes. After this, the intensity decreases in the same sine-wave like manner and eventually reaches zero after another 30 minutes passes.

What symptoms would I experience when the above stimulation is at maximum intensity?

Other facts:

The more intense a stimulus, the higher the firing rate of the neurons in a sensory receptor.

It’s important to note that sensory receptors in *efferent* nerves of any kind are NOT directly stimulated to any extent. In addition, all C-fibers in the body remain completely un-stimulated and relaxed.

Tactile = Pertaining only to sense of touch [including temperature, pressure, pain, tickle, vibrations, movement, position, location etc.]. *Not* including any visual, auditory, gustatory, olfactory perceptions or any sensations associated with the sense of balance.

Peripheral = pertaining only to the peripheral nervous system and not the central nervous system.

Somatic = pertaining only to the somatic nervous system and not the visceral, autonomic, or enteric nervous systems


Quotes from the above site:

"An A-delta fiber responds to either mechanical stimuli or temperature stimuli in the painful realm and produces the acute sensation of sharp, bright pain."

"By contrast, a C fiber can respond to a broad range of painful stimuli, including mechanical, thermal or metabolic factors. The pain produced is slow, burning, and long lasting."


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Reply Sun 30 Oct, 2011 10:33 am
@Green Xenon,
I think many of us understand your desire to write HARD science fiction (Science fiction backed by real world science fact and theory. It's my favorite form of literature to read.)

But not to belabor the point, the questions you ask are either so far out of any range of expertise (medical and biological fields of study) that no one can possibly comprehend your postgraduate/doctoral level science/intentions and thus your questions you are asking here. Or that these theories and direction of the science you are aiming for are so fantastical and impossible reproduce or formulate and to follow or understand that these further questions are leaving our experts confused and befuddled.

I think you need to aim higher by going to a local medical university and picking the minds of a few doctorates in advanced theoretical biology or medicine. Good luck with your research.
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Reply Wed 28 Dec, 2011 02:27 am
@Green Xenon,
this is SF?

Speculative fiction Is NOT specialist science.
The Tsar has it right.

Go to somewhere where specialised bio is of interest. AS we have not the time or interest in the microcosmic function of cells and proteins. Well
Your work is the base for our speculation.

Wrong forum MATE

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