@DrewDad,
It is precisely because i have a good conception of the size of the universe that i find these theses so implausible. The nearest star to our Sol is, i believe, seven light years away. Therefore, so send a "manned" expedition there at a significant fraction of the speed of light (assuming for the sake of discussion, and only for the sake of discussion, that we will achieve this any time soon, even within 200 years), such as 80%, would still require that the participants have provision for nine years of microgravity and exposure to cosmic radiation. That's why what you describe as bumps in the road are really very, very deep canyons to be crossed.
The point about five thousand years is to point up just how long your hive queen would likely have to live, or just how many generations of hive queens would have to pursue the same goal, while maintaining complete control of the hive despite encouraging innovative thought, in order to arrive at a level of technological sophistication necessary for interstellar space faring.
Believe me when i say that i've been giving a great deal of thought to the alleged Fermi paradox for more than 30 years. The idea of a hive society is one of the first things which occurred to me, and therefore, one of the first ideas which i was able to logically shoot down.
I'm not putting any limits on anything. But societies can do and always will put limits on how their resources will be deployed, and it ought to be abundantly clear after 50 years of space programs that society, either our society, or the Russians, or the Chinese, or the Japanese, or the Europeans, have little interest in deploying huge amounts of resources for ventures off the planet.
Interstellar space faring involving thousands of meat machines represents an off-planet venture on a scale which would require virtually all of the planets "disposable" resources for a very long time. I doubt that it will happen in 200 years, or even 2000 years. It might happen some day, but i sincerely doubt that it will happen any time soon. If it happens, it will very likely be as a result of incremental efforts over a very long period of time.
There is good inferential evidence that the Irish reached and set up a modest colony on Greenland as long ago as the seventh century. More likely, though, it was not until the late eighth century, and response to the scourge of the Norse. Erik Raudi (Erik the Red) did not explore Greenland and Baffin Island until 981-984. He set up his Greenland colony in 985. Bjarni Herjolfsson coasted the Newfoundland coast late in that year, but it was not until twelve years later that Leif Eriksson consulted with Bjarni, and sailed directly to Newfoundland, where he found his "Vinland the Good." It was five years or more until Thorfinn Karlsefni, Thorvald Eriksson and Freydis Eriksdottir set out on their own expedition to find Leif's Vinland. (Leif was pouting and wouldn't tell them at what latitude it lay--they never found it.)
Basque, English and Portuguese whalers, sealers and fisherman began to exploit the Grand Banks and Belle Isle Strait in the 15th and 16th centuries, and landed on the Great Northern Peninsula of Newfoundland to salt down their catches. A Dutch whaler which landed near Herjolfness in southern Greenland in the mid-15the century found the corpse of what was probably the last surviving Norse resident. The English did not establish a genuine colony on Newfoundland until 1610.
The technology was not lacking. In fact, the Norse ship, the knorr, with which all of the voyages--Erik Raudi, Bjarni Herjolfsson, Thorfinn Karlsefni--were made, was superior to anything which would be produced for five or six hundred years. In the 1890s, the Norwegians built a replica of the Gokstad ship, a type known as a karva, which was a cross between the knorr and a viking long ship (viking long ships were a sailor's nightmare, and no sailor in his right mind would go to sea in one, they were only good for coasting voyages--but the karva resolved many of their fatal flaws). The Norwegians sailed it to North America for the Columbian Exhibition in Chicago. Sailing form Bergen on April 30, 1893, they reached Newfoundland on May 27th--a cruise most Newfoundland schooner captains would have been proud to have made. In the 1930s, another replica of a Norse ship was built, a 60 foot knorr (most of the larger sea-trading knorrs were 100 foot ships). Like the Gokstad replica, it was made of the same materials as the original, and rigged and sailed exactly as those were. It sailed exactly on the course that Columbus followed in 1492, and beat his sailing time by almost one third--they routinely ran off the same number of nautical miles in three days that it took Columbus four or four and half days to accomplish.
The technology was not lacking--the will to make the effort was the problem. Even religious fervor was not enough. The last European expedition to Greenland before the Basque and Portuguese fishermen arrived on the scene was sent in the 14th century to find out if it were true that the Greenlanders had turned pagan. The expedition never returned (some scholars believe that this expedition made the Kennsington Stone which was found in Minnesota), and no further efforts were made to find the Greenlanders, or to send out a bishop or any more priests.
It was not until John Cabot's 1497 voyage reported that the cod were so thick on the Grand Banks that you could get out and walk that any European power became interested (a little hyperbole is understandable under the circumstances). Even then, it was more than 80 years before England claimed Newfoundland, and more than a century before a colony was even established.
Now you can argue all you want against the lessons of history, but the point is that these matters are not determined by technology nor the state of advancement of science. They don't even need to be. The Norse couild not find longitude, they didn't have compasses and they didn't even have an astrolabe--they used a notched stick to find latitude, and that's what Leif Eriksson used to find his Vinland after he talked to Bjarni Herjolfsson. The delay of literally centuries was occassioned by European rulers who had other things on their minds, and who had populations who were equally uninterested, and whose wishes had to be taken into consideration, whether or not kings claimed to rule by divine right.
So if you can explain to me how you can get the people of this planet to agree to extraordinary sacrifices of money, time and other resources for two centuries in order to send an expedition into the wild black yonder, maybe i'll believe that something like that will be accomplished in 200 years. Like it or not, our own experience is all we have to go on. And the outlook form that vantage point ain't good.