You like hard questions dont you ?
There are four basic elements in living chenistry : carbon, hydrogen, oxygen and nitrogen.
These combine in various ways to form amino acids. Amino acids are used by life to perform fuctions just as they are, and also to build bigger and better life sustaining structures... proteins, for example.
Proteins are amino acids glued into one long chain - sideways thou shall not grow - but they have a secondary structure which is the way they curl and twist. Many proteins once they have assumed their secondary structure stay that way. If you are bitten by a snake, it will be a protein that causes the damage. Proteins account for the biggest single amount of compounds in your body after water is removed, probably about half of your dry weight.
Special proteins that can change shape (usually only once) are called prions. Prions are believed to cause some diseases, Mad Cow disease being one that comes to mind. Where the amino acids join, prions invade and use the mechanism to manufacture themselves.
By adding phosphorus to our four biggies mentioned above at the amino acids level, we can make nucleic acids which are very large molecules in a chain like structure. Two variants of nucleic acids are DNA and RNA. DNA is essential for cellular life, whereas RNA is the structure for viruses. Both DNA and RNA use amino acids in their housekeeping. This is where prions have an effect on life. And that is the connection.